舒芬太尼和右美托咪定预防男性麻醉后导尿管相关膀胱不适的效果

Effect of Sufentanil and Dexmedetomidine on Preventing Catheter-related Bladder Discomfort after Anesthesia in Male

目的:探讨舒芬太尼和右美托咪定预防男性麻醉后导尿管相关膀胱不适的效果。方法:选择2019年1月—2022年10月沭阳中兴医院收治的82例全身麻醉手术需留置导尿管患者作为研究对象,依照随机数表法将患者分为对照组(n=41)与研究组(n=41)。对照组给予舒芬太尼,研究组给予舒芬太尼与右美托咪定。比较两组术后不同时间膀胱不适[视觉模拟评分法(VAS)评分]、血流动力学指标[平均动脉压(MAP)、心率(HR)]及不良反应发生情况。结果:两组术后18 h、36 h、48 h的VAS评分高于术后6 h,两组术后36 h的VAS评分高于术后18 h,两组术后48 h的VAS低于术后36 h,差异有统计学意义(P<0.05);两组术后6 h的VAS评分比较,差异无统计学意义(P>0.05);研究组术后18 h、36 h、48 h的VAS评分低于对照组,差异有统计学意义(P<0.05)。术前,两组MAP、HR比较,差异无统计学意义(P>0.05);术后1 h,两组MAP、HR均高于术前,但研究组低于对照组,差异有统计学意义(P<0.05)。研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:舒芬太尼与右美托咪定预防男性麻醉后导尿管相关膀胱不适效果确切,可改善血流动力学,降低不良反应发生率。

Objective:To explore the effect of Sufentanil and Dexmedetomidine on preventing catheter-related bladder discomfort after anesthesia in male.Method:A total of 82 patients underwent general anesthesia surgery requiring indwelling catheters who treated in Shuyang Zhongxing Hospital from January 2019 to October 2022 were selected as the study objects,and they were divided into the control group(n=41)and the study group(n=41)according to the random number table method.The control group was treated with Sufentanil,and the study group was treated with Sufentanil and Dexmedetomidine.The bladder discomfort[visual analogue scale(VAS)score],hemodynamic indexes[mean arterial pressure(MAP),heart rate(HR)]at different time after operation and adverse reactions were compared between two groups.Result:The VAS scores of two groups at 18 h,36 h and 48 h after operation were higher than those at 6 h after operation,the VAS scores of two groups at 36 h after operation were higher than those at 18 h after operation,the VAS scores of two groups at 48 h after operation were lower than those at 36 h after operation,and the differences were statistically significant(P<0.05);there was no significant difference in VAS score between two groups at 6 h after operation(P>0.05);the VAS scores of the study group at 18 h,36 h and 48 h after operation were lower than those of the control group,and the differences were statistically significant(P<0.05).Before operation,there were no significant difference in MAP and HR between two groups(P>0.05);at 1 h after operation,MAP and HR in two groups were higher than those before operation,but which in the study group were lower than the control group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Sufentanil and Dexmedetomidine have a definite effect on preventing catheter-related bladder discomfort after anesthesia in male,which can improve hemodynamics and reduce the incidence of adverse reactions.