脓毒症患者肠道微生态的研究进展

Research progress of intestinal microecology in patients with sepsis

脓毒症是一种严重的感染性疾病,近年来其发病率和病死率呈上升趋势,严重威胁患者的生命安全,加重了社会经济负担。有研究表明,肠道微生态在脓毒症的发生和发展中起到关键作用,包括引起肠道菌群及有益菌群的比例失调、肠道免疫反应和破坏肠道黏膜屏障功能等。

Sepsis is a serious infectious disease,and its morbidity and mortality are on the rise in recent years,which seriously threatens the life safety of patients and increases the social and economic burden.Previous studies have shown that intestinal microecology plays a key role in the occurrence and development of sepsis,including the imbalance of intestinal flora and beneficial flora,intestinal mucosal barrier function and intestinal immune response.