摘要
抑郁症是一种高发病率、高致残率、高死亡率、严重影响人类生存质量的精神疾病。睡眠障碍不仅仅只是抑郁症的伴随症状,还是抑郁症的先兆表现,更是抑郁症治疗后的残余症状,可以用来预测抑郁症发生和判断其预后。本文从炎症反应、昼夜节律和神经递质通道等方面对抑郁症与睡眠障碍的发生机制,以及对抑郁性睡眠障碍的药物、心理、运动等常用治疗方法进行综述,旨在为其预防和治疗提供参考依据。
Depression is a mental illness with high morbidity,high disability rate,high mortality rate and has serious impact on the quality of human life.Sleep disorders are not only a symptom of depression,but also a precursor manifestation of depression and a residual symptom after depression treatment,which can be used to predict the occurrence and prognosis of depression.This article reviews the mechanism of depression and sleep disorders and the treatment of depressive sleep disorders from the aspects of inflammatory response,circadian rhythm and neurotransmitter pathways so as to provide reference for its prevention and treatment.
作者
傅希雅
郭琪
FU Xiya;GUO Qi(Department of Rehabilitation Medicine,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China;Department of Sport Rehabilitation,Shanghai University of Sport,Shanghai 200438,China)
出处
《上海医药》
2024年第1期55-59,共5页
Shanghai Medical & Pharmaceutical Journal
基金
国家自然科学基金资助项目(81372118)
上海市青年科技英才扬帆计划项目(20YF141820)。
关键词
抑郁症
睡眠障碍
机制
治疗
depression
sleep disorder
mechanism
treatment
