八珍汤联合肠内营养治疗长期卧床伴气血亏虚型贫血患者的临床疗效分析

Analysis of the Clinical Efficacy of Bazhen Decoction Combined with Enteral Nutrition in the Treatment of Patients with Long-Term Bedridden Anemia with Qi and Blood Deficiency

目的:探讨八珍汤在治疗长期卧床伴气血亏虚型贫血患者中的价值。方法:将入组患者随机分为八珍汤组和对照组,对照组予常规治疗+肠内营养支持治疗,八珍汤组在此基础上增加八珍汤益气养血,所有患者疗程均为14天。观察两组患者治疗后的总有效率,将治疗后RBC、Hb、SI、SF等各项指标进行比较,并对治疗后出现的气血亏虚证和消化道不良反应进行综合评价。结果:八珍汤组的临床疗效为86.67%,对照组的临床疗效为60.00%,八珍汤组显著优于对照组。两组患者治疗后的气血亏虚证的中医证候分数较治疗前有所下降,八珍汤组和对照组之间存在显著差别(P<0.05);治疗14天后,八珍汤组在消化道不良反应方面的中医证候分数显著低于对照组(P<0.05);治疗后,两组患者的贫血指标均较治疗前有所改善,且八珍汤组较对照组有明显统计学差异(P<0.05)。结论:八珍汤联合肠内营养对治疗长期卧床伴气血亏虚型贫血有较理想的疗效,值得临床推广。

Objective:To investigate the value of Bazhen decoction in the treatment of patients with long-term bedridden anemia with qi and blood deficiency.Methods:The enrolled patients were randomly divided into Bazhen decoction group and control group,the control group was given conventional treatment+enteral nutrition supportive treatment,and the Bazhen decoction group was supplemented with Bazhen decoction to nourish qi and nourish blood,and the course of treatment for all patients was 14 days.The total effective rate of the two groups was observed,and the RBC,Hb,SI,SF and other indexes were compared after treatment,and the qi and blood deficiency syndrome and gastrointestinal adverse reactions after treatment were comprehensively evaluated.Results:The clinical efficacy of the Bazhen decoction group was 86.67%,and that of the control group was 60.00%,and the Bazhen decoction group was significantly better than that of the control group.There was a significant difference between the Bazhen decoction group and the control group(P<0.05)after treatment,and the TCM pattern score of gastrointestinal adverse reactions in the Bazhen decoction group was significantly lower than that of the control group(P<0.05)after 14 days of treatment.After treatment,the anemia indexes of the two groups were improved compared with those before treatment,and there was a significant statistical difference between the Bazhen decoction group and the control group(P<0.05).Conclusion:Bazhen decoction combined with enteral nutrition has an ideal effect on the treatment of long-term bed rest with qi and blood deficiency anemia,which is worthy of clinical promotion.