系统规范化干预在脑胶质瘤手术患者中的应用效果

Application effect of systematic standardized intervention in patients undergoing surgery for glioma

目的 探讨系统规范化干预在脑胶质瘤手术患者中的应用效果。方法 根据干预方法的不同将110例脑胶质瘤手术患者分为对照组(n=55,常规干预)和观察组(n=55,在对照组的基础上进行系统规范化干预)。比较两组患者的心理状态[焦虑自评量表(SAS)、抑郁自评量表(SDS)]、应激反应指标[促肾上腺皮质激素(ACTH)、去甲肾上腺素(NE)、皮质醇(Cor)]、神经功能缺损情况[美国国立卫生研究院卒中量表(NIHSS)]、生活质量[生活质量综合评定问卷(GQOLI-74)]及满意度。结果 干预后,两组患者SAS、SDS、NIHSS评分均低于本组干预前,观察组患者SAS、SDS、NIHSS评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者ACTH、NE、Cor水平均高于本组干预前,观察组患者ACTH、NE、Cor水平均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者角色功能、心理功能、躯体功能、社会功能评分均高于本组干预前,观察组患者角色功能、心理功能、躯体功能、社会功能评分均高于对照组,差异均有统计学意义(P﹤0.05)。观察组患者总满意度高于对照组(P﹤0.05)。结论 系统规范化干预可有效改善脑胶质瘤手术患者的心理状态,减轻应激反应,促使患者神经功能恢复,提高患者生活质量和满意度。

Objective To explore the effect of systematic standardized intervention in patients undergoing surgery for glioma.Method A total of 110 glioma patients who underwent surgical treatment were divided into control group(n=55,received routine intervention) and observation group(n=55,received systematic standardized intervention on the basis of the control group) according to different intervention methods.The psychological status [self-rating anxiety scale(SAS),self-rating depression scale(SDS)],stress response indicators [adrenocorticotropic hormone(ACTH),norepinephrine(NE),cortisol(Cor)],neurological deficit [National Institute of Health stroke scale(NIHSS)],quality of life [generic quality of life inventory-74(GQOLI-74)] and satisfaction were compared between the two groups.Result After intervention,the SAS,SDS and NIHSS scores in both groups were lower than those before intervention,with lower scores in the observation group than those in the control group(P<0.05).After intervention,the levels of ACTH,NE and Cor in both groups were higher than those before intervention,with lower levels in the observation group than those in the control group(P<0.05).After intervention,the scores of role function,psychological function,physical function and social function in both groups were higher than those before intervention,with higher scores in the observation group than those in the control group(P<0.05).The total satisfaction rate of the observation group was higher than that of the control group(P<0.05).Conclusion Systematic standardized intervention for glioma patients undergoing surgery can improve psychological status,reduce stress response,promote the recovery of neurological function,and improve the quality of life and satisfaction.