司米护齿涂剂治疗正畸过程中牙釉质脱矿的有效性和安全性分析

Efficacy and safety analysis of Simi tooth coating agent in the treatment of enamel demineralization during orthodontic treatment

目的 探讨司米护齿涂剂治疗正畸过程中牙釉质脱矿(ED)的临床效果。方法 择取68例正畸治疗的错颌畸形患者,随机分为对照组与实验组,每组34例。对照组给予多乐氟氟化钠护齿剂,实验组给予司米护齿涂剂。对比两组治疗后的牙周情况[菌斑指数、改良出血指数(mBI)]、ED发生率及牙釉质脱矿指数(EDI)。结果 治疗后6、9、12个月,实验组的菌斑指数分别为(1.98±0.13)、(1.95±0.20)、(1.00±0.11),mBI分别为(1.65±0.12)、(1.19±0.13)、(0.92±0.06)均明显低于对照组的(2.65±0.15)、(2.48±0.22)、(1.71±0.15)与(2.06±0.14)、(1.53±0.10)、(1.09±0.05)(P<0.05);治疗后6、9、12个月,实验组的ED发生率分别为14.71%、8.82%、0,均明显低于对照组的41.18%、29.41%、11.76%(P<0.05);实验组治疗后6、9、12个月的EDI分别为(16.35±1.20)、(13.58±1.47)、(9.26±1.02),均明显低于对照组的(20.18±1.62)、(17.50±1.53)、(15.14±1.15)(P<0.05)。结论 对正畸治疗的错颌畸形患者给予司米护齿涂剂安全有效,能够有效预防ED事件,改善牙周指标,值得采纳。

Objective To investigate the clinical effect of Simi tooth coating agent in the treatment of enamel demineralization(ED) during orthodontic treatment.Methods 68 malocclusion patients with orthodontic treatment were selected and randomly divided into a control group and an experimental group,with 34 cases in each group.The control group was given Duraphat 50 mg/ml Dental Suspension,and the experimental group was given Simi tooth coating agent.The periodontal status [plaque index,modified bleeding index(mBI)],incidence of ED and enamel demineralization index(EDI) were compared between the two groups after treatment.Results At 6,9 and 12 months after treatment,the plaque index in the experimental group were(1.98±0.13),(1.95±0.20),(1.00±0.11),and mBI were(1.65±0.12),(1.19±0.13),(0.92±0.06),which were significantly lower than those of(2.65±0.15),(2.48±0.22),(1.71±0.15) and(2.06±0.14),(1.53±0.10),(1.09±0.05) in the control group(P<0.05).At 6,9 and 12 months after treatment,the incidence rates of ED in the experimental group were 14.71%,8.82% and 0,respectively,which were significantly lower than those of 41.18%,29.41%and 11.76% in the control group(P<0.05).EDI in the experimental group at 6,9 and 12 months after treatment were(16.35±1.20),(13.58±1.47) and(9.26±1.02),respectively,which were significantly lower than those of(20.18±1.62),(17.50±1.53) and(15.14±1.15) in the control group(P<0.05).Conclusion Simi tooth coating agent for malocclusion patients undergoing orthodontic treatment is safe and effective,and can effectively prevent ED events,improve periodontal indicators,and is worth adopting.