芪术健脾护膜汤对胃溃疡患者临床症状评分及不良反应发生率的影响分析

Effect analysis of Qizhu Jianpi Humo Decoction on clinical symptom score and incidence of adverse reactions in the treatment of patients with gastric ulcer

目的 探析胃溃疡患者使用芪术健脾护膜汤治疗的效果以及对临床症状评分、不良反应发生率的影响。方法 84例胃溃疡患者,采用随机数字表法分为对照组与观察组,每组42例。对照组患者使用常规西药治疗,观察组患者在对照组基础上加用芪术健脾护膜汤治疗。比较两组患者临床疗效、不良反应发生率及治疗前后临床症状评分。结果 观察组治疗总有效率95.24%明显高于对照组的78.57%,差异具有统计学意义(P<0.05)。治疗1个月后,两组腹部疼痛、反胃、嗳气和灼热评分均低于治疗前,且观察组腹部疼痛、反胃、嗳气和灼热评分分别为(0.66±0.11)、(0.62±0.09)、(0.74±0.16)、(0.80±0.27)分,低于对照组的(1.17±0.13)、(1.03±0.12)、(1.12±0.18)、(1.13±0.20)分,差异具有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义(χ^(2)=0.213,P=0.645>0.05)。结论 对胃溃疡患者使用芪术健脾护膜汤治疗可获得较好的效果,能够显著缓解各项临床症状,且不良反应较少,具有较高的临床应用价值。

Objective To explore the effect of Qizhu Jianpi Humo Decoction on patients with gastric ulcer and its influence on clinical symptom score and incidence of adverse reactions.Methods 84 patients with gastric ulcer were randomly divided into a control group and an observation group,with 42 cases in each group.The patients in the control group were treated with conventional western medicine.On this basis,the observation group was treated with Qizhu Jianpi Humo Decoction.The clinical efficacy,clinical symptom score and incidence of adverse reactions of the two groups were compared.Results The total effective rate of the observation group was 95.24% significantly higher than 78.57% of the control group,and the difference was statistically significant(P<0.05).After 1 month of treatment,the scores of abdominal pain,nausea,belching and burning in both groups were lower than those before treatment;and the scores of abdominal pain,nausea,belching and burning in the observation group were(0.66±0.11),(0.62±0.09),(0.74±0.16) and(0.80±0.27) points,which were lower than those of(1.17±0.13),(1.03±0.12),(1.12±0.18) and(1.13±0.20) points in the control group.The difference was statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(χ^(2)=0.213,P=0.645>0.05).Conclusion The treatment of gastric ulcer patients with Qizhu Jianpi Humo Decoction can obtain good results,can significantly alleviate various clinical symptoms,and has less adverse reactions.It has high clinical application value.