表观遗传调控植物雄性生殖系细胞发育的研究进展

Advances in epigenetic regulation of plant male germline cell development

植物雄性生殖系细胞在发育过程中需经历染色质重塑、组蛋白修饰、DNA甲基化以及小RNA等途径所介导的表观遗传重编程。现已发现诸多基因参与塑造雄性生殖系细胞的表观遗传状态,并调控植物雄性育性。此外,随着各类组学技术的不断进步,一系列关于雄性生殖系细胞在不同发育阶段的特定表观遗传信息被揭示。本文简要梳理了近年来植物雄性生殖系细胞发育过程中表观遗传动态及其所涉及的分子机理的研究进展,并对表观遗传调控植物雄性生殖系细胞发育的后续研究进行了展望。

Male germline cells in plants undergo epigenetic reprogramming mediated by chromatin remodeling,histone modification,DNA methylation,and small RNA during development.Many genes are involved in shaping the epigenetic state of male germline cells and regulating plant male fertility.Recent advances in multi-omics techniques have helped elucidate specific epigenetic profiles of male germline cells at different stages of development.In this review,we summarize recent advances in epigenetic dynamics and molecular mechanisms involved in the development of male germline cells in plants and discuss prospects for future studies on the epigenetic regulation of this developmental process.