期刊文献+

A novel intelligent chromo capsule endoscope for the diagnosis of neoplastic lesions in the gastrointestinal tract

原文传递
导出
摘要 Background:Chromoendoscopy has not been fully integrated into capsule endoscopy.This study aimded to develop and validate a novel intelligent chromo capsule endoscope(ICCE).Methods:The ICCE has two modes:a white-light imaging(WLI)mode and an intelligent chromo imaging(ICI)mode.The performance of the ICCE in observing colors,animal tissues,and early gastrointestinal(GI)neoplastic lesions in humans was evaluated.Images captured by the ICCE were analysed using variance of Laplacian(VoL)values or image contrast evaluation.Results:For color observation,conventional narrow-band imaging endoscopes and the ICI mode of the ICCE have similar spectral distributions.Compared with the WLI mode,the ICI mode had significantly higher VoL values for animal tissues(2.15461.044 vs 3.80061.491,P=0.003),gastric precancerous lesions and early gastric cancers(2.24260.162 vs 6.64260.919,P<0.001),and colon tumors(3.89661.430 vs 11.88267.663,P<0.001),and significantly higher contrast for differentiating tumor and non-tumor areas(0.06960.046 vs 0.14460.076,P=0.005).More importantly,the sensitivity,specificity,and accuracy of the ICI mode for early GI tumors were 95.83%,91.67%,and 94.64%,respectively,which were significantly higher than the values of the WLI mode(78.33%[P<0.001],77.08%[P=0.01],and 77.98%[P<0.001],respectively).Conclusions:We successfully integrated ICI into the capsule endoscope.The ICCE is an innovative and useful tool for differential diagnosis based on contrast-enhanced images and thus has great potential as a superior diagnostic tool for early GI tumor detection.
出处 《Gastroenterology Report》 SCIE CSCD 2023年第1期291-299,共9页 胃肠病学报道(英文)
基金 supported by the National Natural Science Foundation of China[grant numbers 82170571,82100569,and 81974068] the Natural Science Foundation of Hubei Province of China[grant number 2021CFB122].
  • 相关文献

参考文献4

二级参考文献39

  • 1Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM.Estimates of worldwide burden of cancer in 2008: GLOBOCAN2008. Int J Cancer 2010; 127: 2893-2917 [PMID: 21351269 DOI:10.1002/ijc.25516].
  • 2Soetikno R, Kaltenbach T, Yeh R, Gotoda T. Endoscopic mucosalresection for early cancers of the upper gastrointestinal tract. JClin Oncol 2005; 23: 4490-4498 [PMID: 16002839 DOI: 10.1200/JCO.2005.19.935].
  • 3Ezoe Y, Muto M, Uedo N, Doyama H, Yao K, Oda I, Kaneko K,Kawahara Y, Yokoi C, Sugiura Y, Ishikawa H, Takeuchi Y, KanekoY, Saito Y. Magnifying narrowband imaging is more accurate thanconventional white-light imaging in diagnosis of gastric mucosalcancer. Gastroenterology 2011; 141: 2017-2025.e3 [PMID:21856268 DOI: 10.1053/j.gastro.2011.08.007].
  • 4Tao G, Xing-Hua L, Ai-Ming Y, Wei-Xun Z, Fang Y, Xi W, Li-Yin W, Chong-Mei L, Gui-Jun F, Hui-Jun S, Dong-Sheng W, YueL, Xiao-Qing L, Jia-Ming Q. Enhanced magnifying endoscopy fordifferential diagnosis of superficial gastric lesions identified withwhite-light endoscopy. Gastric Cancer 2014; 17: 122-129 [PMID:23494118 DOI: 10.1007/s10120-013-0250-1].
  • 5Maki S, Yao K, Nagahama T, Beppu T, Hisabe T, Takaki Y, HiraiF, Matsui T, Tanabe H, Iwashita A. Magnifying endoscopy withnarrow-band imaging is useful in the differential diagnosis betweenlow-grade adenoma and early cancer of superficial elevated gastriclesions. Gastric Cancer 2013; 16: 140-146 [PMID: 22592604 DOI:10.1007/s10120-012-0160-7].
  • 6Miwa K, Doyama H, Ito R, Nakanishi H, Hirano K, InagakiS, Tominaga K, Yoshida N, Takemura K, Yamada S, KanekoY, Katayanagi K, Kurumaya H, Okada T, Yamagishi M. Canmagnifying endoscopy with narrow band imaging be useful forlow grade adenomas in preoperative biopsy specimens- GastricCancer 2012; 15: 170-178 [PMID: 22407064 DOI: 10.1007/s10120-011-0093-6].
  • 7Ezoe Y, Muto M, Horimatsu T, Minashi K, Yano T, Sano Y, ChibaT, Ohtsu A. Magnifying narrow-band imaging versus magnifyingwhite-light imaging for the differential diagnosis of gastric smalldepressive lesions: a prospective study. Gastrointest Endosc 2010;71: 477-484 [PMID: 20189506 DOI: 10.1016/j.gie.2009.10.036].
  • 8Kato M, Kaise M, Yonezawa J, Toyoizumi H, Yoshimura N,Yoshida Y, Kawamura M, Tajiri H. Magnifying endoscopy withnarrow-band imaging achieves superior accuracy in the differentialdiagnosis of superficial gastric lesions identified with white-lightendoscopy: a prospective study. Gastrointest Endosc 2010; 72:523-529 [PMID: 20598685 DOI: 10.1016/j.gie.2010.04.041].
  • 9Yao K, Anagnostopoulos GK, Ragunath K. Magnifyingendoscopy for diagnosing and delineating early gastric cancer.Endoscopy 2009; 41: 462-467 [PMID: 19418401 DOI: 10.1055/s-0029-1214594].
  • 10Wanders LK, East JE, Uitentuis SE, Leeflang MM, DekkerE. Diagnostic performance of narrowed spectrum endoscopy,autofluorescence imaging, and confocal laser endomicroscopy foroptical diagnosis of colonic polyps: a meta-analysis. Lancet Oncol2013; 14: 1337-1347 [PMID: 24239209 DOI: 10.1016/S1470-2045].

共引文献114

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部