常见环境污染物致斑马鱼机体氧化应激的研究进展

Research progress on oxidative stress induced by common environmental pollutants in zebrafish (Danio rerio)

近年来,随着我国城市化和工业化进程的快速发展,水环境污染问题日趋严重,对生态环境和人类健康构成潜在威胁.氧化应激是机体促氧化物产生和清除之间出现失衡的一种状态,被认为是影响许多疾病发生发展的重要因素,是水环境污染物对生物体产生毒性的重要途径之一.本文基于重金属、农药和新兴污染物等常见环境污染物对斑马鱼所产生的氧化应激反应进行综述,以期为开展污染物损伤生物体的监控预警及疾病预防提供一定参考依据.

In recent years,with the rapid development of urbanization and industrialization,the problem of water environment pollution has become increasingly serious,which poses a potential threat to the ecological environment and human health.Oxidative stress is a state of imbalance between the production and removal of prooxidants,which is considered to be an important factor affecting the occurrence and development of many diseases and one of the important ways for water environmental pollutants to produce toxicity to organisms.In this paper,the oxidative stress reactions of zebrafish caused by common environmental pollutants such as heavy metals,pesticides,and emerging pollutants were reviewed to provide some reference for the monitoring and early warning of pollutant damage organisms and disease prevention.