补益为主植物饮品早早睡神经药理学作用机制研究

Study on the Neuropharmacological Mechanism of ZaoZaoShui with MainTonifying Plant Drinks

目的:研究补益为主植物饮品早早睡的药理学活性成分,了解其作用机制。方法:将植物饮品早早睡委托给有多个国内外权威机构资质认证的深圳市计量质量检测研究院,按相关国家标准法及《保健食品检验与评价技术规范》(2003年版)进行实验检测。结果:植物饮品早早睡含有多种氨基酸、钙、维生素B6、黄酮、总皂甙等。结论:基于失眠多虚理论,以补益气血、健脾滋肝肾、养心安神组方的植物饮品早早睡安神作用可能的神经药理学机制之一,是通过其所含的生物活性物质维护神经元的正常代谢、调节中枢神经及相关神经递质、镇静催眠、神经保护等神经系统作用而达到的。

Objective To study the pharmacological bioactive substances and mechanism of ZaoZaoShui(ZZS)with main tonifying plant drinks.Methods The plant drinks ZZS was entrusted to Shenzhen Academy of Metrology and Quality Inspection,which had been certified by multiple domestic and foreign authoritative institutions.Experimental testing was conducted in accordance with relevant national standards and Technical Specifications for Inspection and Evaluation of Health Food(2003 edition).Results The plant drinks ZZS contained a variety of amino acids,calcium,vitamin B6,flavonoids,saponins and so on.Conclusion Based on the theory of insomnia with multiple deficiencies,one of the possible neuropharmacological mechanisms of the plant drinks ZZS with tonifying Qi-blood,strengthening spleen and nourishing liver and kidney,and nourishing heart and calming mind were achieved by maintaining the normal metabolism of neurons,regulating the central nervous system and related neurotransmitters,sedating hypnosis,neuroprotection and other nervous system functions.