核素显像在神经母细胞瘤中的临床应用及进展

Clinical applications and progress of radionuclide imaging in neuroblastoma

神经母细胞瘤是儿童最常见的颅外实体瘤, 不同分期的预后差异较大, 而其危险度分期系统完全基于影像学判断。核素显像在多种肿瘤的诊断和分期中发挥着重要作用, 对神经母细胞瘤的早期诊断及分期也具有重要意义。目前用于神经母细胞瘤的显像剂主要包括儿茶酚胺受体类、葡萄糖代谢类、生长抑素受体类等, 该文主要讨论这些显像剂在神经母细胞瘤诊断中的应用价值及研究进展。

Neuroblastoma is the most common extracranial solid tumor in children.The prognosis of different stages varies greatly,and its risk staging system is completely based on imaging.Radionuclide imaging plays an important role in the diagnosis and staging of various tumors,and it is also of great significance in the early diagnosis and staging of neuroblastoma.At present,imaging agents used for neuroblastoma mainly include catecholamine receptor,glucose metabolism,somatostatin receptor,etc.This article mainly discusses the application value and research progress of these imaging agents in the diagnosis of neuroblastoma.