少动鞘氨醇单胞菌合成结冷胶研究进展

Advances in the biosynthesis of gellan gum by Sphingomonas paucimobilis

结冷胶是少动鞘氨醇单胞菌(Sphingomonas paucimobilis)产生的一种细菌胞外多糖,耐热、耐酸性良好,具有优越的凝胶性能,广泛应用于食品、医药和化工等领域。通过代谢调控可使结冷胶改性并提高产量,但目前关于结冷胶在生物合成和代谢调控方面的研究较少。该文结合近年来国内外结冷胶研究现状,总结了少动鞘氨醇单胞菌产结冷胶的生物合成途径及其代谢调控,期望为结冷胶生产菌株改造提供理论依据。

Gellan gum is a bacterial exopolysaccharide produced by Sphingomonas paucimobilis,which has good heat resistance,acid resistance,and superior gelation properties.It is widely used in food,pharmaceutical,and chemical industries.However,there are few studies on the biosynthesis and metabolic regulation of gellan gum.We summarize the biosynthetic pathway and metabolic regulation of gellan gum production by S.paucimobilis,which is expected to provide a theoretical basis for the modification of gellan gum production strains.