基于数据挖掘探讨高血压合并射血分数保留型心力衰竭的用药规律

Medication Rules for Hypertension with Preserved Ejection Fraction Heart Failure Based on Data Mining

目的/意义运用数据挖掘方法探讨中医药治疗高血压合并射血分数保留型心力衰竭的用药规律和组方特点。方法/过程基于黑龙江中医药大学附属第一医院心血管病一科2019年1月-2022年7月收治的高血压合并射血分数保留型心力衰竭患者中药处方信息建立数据库。采用SPSS Statistics、Moderler软件进行频数、性味归经、功效、关联规则及聚类分析,挖掘组方用药规律。结果/结论中医药治疗高血压合并射血分数保留型心力衰竭多以益气健脾、养心安神为主,辅以化痰止咳平喘,同时注重活血化瘀、利水渗湿,标本兼顾,可为临床用药提供参考。

Purpose/Significance By using data mining methods,the medication rules and prescription characteristics of traditional Chinese medicine(TCM)for treating hypertension with preserved ejection fraction heart failure are discussed.Method/Process The database is established based on the TCM prescription information of hypertensive patients with preserved ejection fraction heart failure admitted to the Cardiovascular Disease Department of the First Affiliated Hospital of Heilongjiang University of Chinese Medicine from January 2019 to July 2022.SPSS Statistics and Moderler software are used to analyze the frequency,taste,meridian tropism,efficacy,association rules,clustering and factor analysis of the prescriptions to explore medication rules.Result/Conclusion TCM in the treatment of hypertension with preserved ejection fraction heart failure is mainly to replenish qi and spleen,nourish the heart and calm the mind,relieve phlegm,relieve cough and asthma,and pay attention to promoting blood circulation and removing blood stasis,promoting water infiltration and dampness,which can reflect the overall concept of TCM and the characteristics of diagnosis and treatment based on syndrome differentiation and provide references for clinical medication.