急性心肌梗死经皮冠状动脉介入治疗预后不良因素的研究现状

Current Research Status of Adverse Prognostic Factors in Acute Myocardial Infarction after Percutaneous Coronary Intervention

急性心肌梗死(AMI)是因冠状动脉急性闭塞、血流中断引起的局部心肌缺血性坏死,主要临床表现为持续性胸骨后疼痛、休克、心律失常和心力衰竭等,并伴有血清心肌酶增高以及心电图改变,病死率较高。临床最常见的AMI手术治疗方法为经皮冠状动脉介入治疗(PCI),影响PCI手术预后效果的因素较多,主要包括血清肌酐水平、心理状态、营养不良、合并糖尿病和血清肌钙蛋白T水平、复流发生率、血管内皮生长因子等。近年来,提升AMI患者PCI手术预后的方法一直是临床AMI治疗的研究重点。

Acute myocardial infarction(AMI)is a local ischemic necrosis of the myocardium caused by acute occlusion of the coronary artery and interruption of blood flow.Its main clinical manifestations include persistent retrosternal pain,shock,arrhythmia,and heart failure etc.,accompanied by elevated serum myocardial enzymes and electrocardiogram changes,with a high mortality rate.The most common surgical treatment for AMI is percutaneous coronary intervention(PCI).There are many factors that affect the prognosis of PCI,including serum creatinine level,mental state,malnutrition,diabetes,serum troponin T level,recurrent rate,vascular endothelial growth factor,etc.In recent years,methods to improve the prognosis of PCI surgery in AMI patients have always been a research focus in clinical AMI treatment.