早发型重度子痫前期伴随胎儿生长受限的相关临床研究

Clinical study on early-onset severe preeclampsia with fetal growth restriction

目的探讨早发型重度子痫前期(EOSP)伴随胎儿生长受限(FGR)的相关结局。方法选取150例EOSP产妇,根据是否伴随FGR为标准,其中75例伴随FGR视为试验组,75例未伴随FGR视为对照组。两组产妇均实施期待疗法,比较两组临床效果。结果两组产妇并发症发生率比较,差异无统计学意义(P>0.05)。与对照组相比,试验组早产率较低,剖宫产率较高(P<0.05),研究组妊娠终止时间(37.15±0.97)周长于对照组的(33.23±1.02)周,两组产后出血率比较,差异无统计学意义(P>0.05)。与对照组相比,试验组新生儿窒息、贫血、死亡、心脏发育不全的比例较低(P<0.05)。两组新生儿窒息发生比例比较,差异无统计学意义(P>0.05)。结论对EOSP伴随FGR产妇实施期待疗法,不仅不会增加并发症发生率,还能够改善母婴结局,应用价值较高。

Objective To investigate the outcomes of early-onset severe preeclampsia(EOsP)with fetal growth restriction(FGR).Methods 150 women with EOSP were selected.According to whether they were accompanied by FGR or not,75 with FGR were considered as the experimental group and 75 without FGR were considered as the control group.Expectant therapy was performed in both groups,and the clinical effect of the two groups was compared.Results There was no significant difference in the incidence of complications between the two groups(P>0.05).Compared with the control group,the preterm birth rate of experimental group was lower and the cesarean section rate was higher(P<0.05).The duration of pregnancy termination in the study group was(37.15±0.97)weeks compared with(33.23±1.02)weeks in the control group.There was no statistical significance in the rate of postpartum hemorrhage between the two groups(P>0.05).Compared with the control group,the rates of neonatal asphyxia,anemia,death and cardiac hypoplasia in experimental group were lower(P<0.05).There was no significant difference in the incidence of neonatal jaundice between the two groups(P>0.05).Conclusion Expectative therapy for women with EOSP accompanied by FGR not only does not increase the incidence of complications,but also can improve the outcome of the mother and child,and has high application value.