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幽门螺杆菌感染在不同糖耐量患者中的变化及临床意义

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摘要 目的 探讨幽门螺杆菌(Hp)在不同糖耐量患者中的变化及临床意义。方法 选取住院和体检的200例受试者。根据糖耐量情况分为2型糖尿病组(T2DM)66例、糖耐量减低组58例和糖耐量正常组76例,分析幽门螺杆菌在不同糖耐量患者中的变化。结果 糖耐量减低组和T2DM组Hp感染率高于糖耐量正常组,且T2DM组Hp感染率高于糖耐量减低组,差异有统计学意义(P<0.05)。Spearman相关分析提示Hp感染与BMI、LDL-C、TC、TG、FBG、FINS、HOMA-IR和HbA1c呈正相关(P<0.05)。Logistic回归分析提示,Hp感染是糖耐量减低(OR=2.001,95%CI 1.457-3.068,P=0.011)和T2DM(OR=2.116,95%CI1.413-3.866,P=0.008)的独立危险因素。结论 随着糖代谢紊乱的加重,Hp感染率逐渐增高,并且Hp感染是IGR和T2DM的独立危险因素。
作者 冉丹
出处 《哈尔滨医药》 2023年第6期59-61,共3页 Harbin Medical Journal
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