摘要
抗性淀粉(resistant starch,RS)作为一种新型膳食纤维,与肠道微生物相互作用,可以促进部分有益菌的生长以及产生短链脂肪酸,有益人体健康。作者综述了抗性淀粉的分类、制备、结构特点与理化性质,以及对慢性肾脏病(chronic kidney disease,CKD)的影响,包括其如何通过调节肠道菌群、减少尿毒症毒素与全身性炎症等缓解肾损伤、延缓慢性肾脏病进程。研究结果为开发具有辅助改善慢性肾脏病功能的抗性淀粉类食品提供了一定的理论依据。
Resistant starch(RS),as a novel dietary fiber,interacts with the gut microbiota,promoting the growth of some beneficial bacteria and the production of short-chain fatty acids,which is beneficial to human health.This review summarizes the classifications,preparations,structural characteristics,and physicochemical properties of resistant starch,as well as its effects on chronic kidney disease,including how it alleviates kidney damage and delays the progression of chronic kidney disease by regulating the gut microbiota,reducing uremic toxins,and systemic inflammation.The research findings provide a theoretical basis for the development of resistant starch-based foods with potential benefits for improving chronic kidney disease.
作者
管骁
夏吉安
张妤
张苏华
宦红娣
任菲
孙宇
郝麒麟
闫雅非
张丽琍
孙注
余治权
GUAN Xiao;XIA Ji’an;ZHANG Yu;ZHANG Suhua;HUAN Hongdi;REN Fei;SUN Yu;HAO Qilin;YAN Yafei;ZHANG Lili;SUN Zhu;YU Zhiquan(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;National Grain Industry(Urban Grain and Oil Security)Technology Innovation Center,University of Shanghai for Science and Technology,Shanghai 200093,China;Department of Nephrology,Jiading District Central Hospital AffiliatedShanghai University of Medicine&Health Sciences,Shanghai 201899,China;The 905th Hospital of People's Liberation Army Navy,Shanghai 200050,China;State Key Laboratory of Food Nutrition and Safety,Tianjin University of Science and Technology,Tianjin 300457,China;School of Food Engineering,Harbin University,Harbin 150086,China;Inner Mongolia Sanzhuliang Natural Oat Industry Co.,Ltd.,Hohhot 010000,China;Anhui Yanzhifang Food Co.,Ltd.,Hefei 231600,China;Inner Mongolia Yangufang Ecological Agriculture Technology(Group)Co.,Ltd.,Hohhot 011700,China)
出处
《食品与生物技术学报》
CAS
CSCD
北大核心
2024年第1期1-12,共12页
Journal of Food Science and Biotechnology
基金
上海市科技兴农重点攻关项目(2021-02-08-00-12-F00780)
上海市优秀学术/技术带头人项目(23XD1430500)。
关键词
抗性淀粉
慢性肾脏病
肠道菌群
resistant starch
chronic kidney disease
gut microbiota
