人工智能技术在阿尔茨海默病诊治中的应用进展

Progress in the application of artificial intelligence in the diagnosis and treatment of Alzheimer's disease

阿尔茨海默病(Alzheimer's disease, AD)是一种慢性进行性神经系统变性疾病,严重影响到患者的认知能力和日常生活功能。随着人工智能技术的发展,越来越多的研究探索如何利用深度学习、卷积神经网络等人工智能技术在阿尔茨海默病的预测、诊断和治疗中快速、高效地发挥作用,涉及到影像学分析、神经心理数据处理、治疗以及智能辅助设备等领域。本文旨在对人工智能技术在阿尔茨海默病中的应用及研究现状进行综述。在这篇综述中,我们汇编了现有的人工智能技术在AD影像数据处理、对AD的预测、在AD治疗以及在AD患者智能辅助设备方面的应用进展,根据系统综述和meta分析首选的系统文献综述及相关研究,2023年7月-8月,在PubMed、知网CHKD、万方数据库及智慧云图书馆中搜索了预先确定的关键词,生成了96个非重复的结果。接下来,我们对96篇论文的标题和摘要进行筛选,之后排除50篇,剩下46篇进行综合分析。人工智能技术在阿尔茨海默病诊治中的应用已较广泛,具有较好的应用前景,但部分缺乏实用性及可推广性,有待更进一步优化。

Alzheimer's disease(AD)is a chronic progressive neurological degenerative disease,which seriously affects the cognitive ability and daily living function of patients.With the advancement of artificial intelligence(AI)technologies,there has been increasing research exploring the rapid and efficient application of deep learning,convolutional neural networks,and other AI techniques in the prediction,diagnosis,and treatment of AD.These applications encompass various areas such as imaging analysis,neuropsychological data processing,treatment,and intelligent assistive devices.This paper aims to review the application and research status of artificial intelligence technology in AD.In this review,we compiled the existing artificial intelligence technology in AD image data processing,AD prediction,in AD treatment and AD patients intelligent auxiliary equipment application progress,according to the systematic review and meta analysis preferred systematic literature review and related studies,in July and August 2023,we searched in PubMed,CHKD,database and the cloud library,this step generated 96 non-repeated results.Next,we screened the titles and abstracts of 96 papers and then excluded 50 papers,leaving 46 for a comprehensive analysis.The application of artificial intelligence technology in the diagnosis and treatment of AD has a good application prospect,but some of them lack practicability and generalization,and need to be further optimized.