桉柠蒎肠溶胶囊在慢性鼻窦炎患者内镜术后治疗中的应用效果分析

Study on the Application Effect of Eucalyptus-pinol Enteric Capsule in the Postendoscopic Treatment of Patients with Chronic Sinusitis

目的:探讨桉柠蒎肠溶胶囊应用于慢性鼻窦炎(CRS)患者内镜术后治疗中的应用效果,为临床提供参考。方法:选取2020年10月—2021年9月凭祥市人民医院收治的96例CRS患者作为研究对象,按摸球法分为两组,对照组(48例)采用常规基础治疗,观察组(48例)采用桉柠蒎肠溶胶囊治疗。比较两组患者临床疗效、炎性因子水平、不良反应。结果:观察组总有效率显著高于对照组,差异有统计学意义(χ^(2)=6.008,P<0.05);治疗后观察组IL-6、TNF-α、hs-CRP水平明显降低,显著低于对照组,差异有统计学意义(t=9.608、11.495、14.751,P<0.05);观察组症状改善时间均显著短于对照组,差异有统计学意义(t=5.250、7.419、8.380、10.626、8.301,P<0.05);观察组不良反应率显著低于对照组,差异有统计学意义(χ^(2)=5.031,P<0.05)。结论:CRS患者内镜术后采用桉柠蒎肠溶胶囊进行治疗,可提高临床疗效,改善炎性因子水平,减少不良反应发生,安全可靠。

Objective:To investigate the efficacy of eucalyptus pinnatifida enteric capsule applied in the postendoscopic treatment of patients with chronic rhinosinusitis(CRS).Methods:96 cases of CRS patients admitted to the hospital from October 2020 to September 2021 were selected as the study subjects and divided into two groups according to the touch-ball method.The control group(48 cases)was treated with conventional basic treatment,and the observation group(48 cases)was treated with eucalyptus-pinol enteric capsule.The clinical efficacy,inflammatory factor levels,and adverse reactions of the two groups were compared.Results:The total effective rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(χ^(2)=6.008,P<0.05).The levels of IL-6,TNF-αand hs-CRP in the observation group were significantly lower than those in the control group after treatment,and the difference was statistically significant(t=9.608,11.495,14.751,P<0.05).The improvement time of symptoms in the observation group were all significantly shorter than that of the control group,and the difference was statistically significant(t=5.250,7.419,8.380,10.626,8.301,P<0.05).The rate of adverse reactions in the observation group was significantly lower than that in the control group,and the difference was statistically significant(χ^(2)=5.031,P<0.05).Conclusion:The treatment of CRS patients with eucalyptus pinnatifida enteric capsule after endoscopy can improve the clinical efficacy,improve the level of inflammatory factors,reduce the occurrence of adverse reactions,and be safe and reliable.