DisCoVisc黏弹剂对白内障患者术后角膜水肿的预防效果

Preventive Effect of DisCoVisc Viscoelastic Aagent on Postoperative Corneal Edema in Cataract Patients

目的:DisCoVisc黏弹剂对白内障患者术后角膜水肿的预防效果。方法:选择2021年3月—2022年3月样本医院收治的102例白内障患者作为研究对象,以随机数表法分成常规组(51例)和实验组(51例)。常规组接受透明质酸钠治疗,实验组接受DisCoVisc黏弹剂治疗。对比两组患者治疗前后角膜内皮细胞、临床疗效、术后28 d角膜水肿情况及不良反应发生情况。结果:治疗后,两组患者角膜内皮细胞均升高,差异有统计学意义(t=3.855,P<0.05);与常规组相比,实验组临床疗效较高,差异有统计学意义(Z=5.254,P<0.05);与术后1 d相比,术后28 d两组患者角膜水肿均降低,差异有统计学意义(χ^(2)=5.258,P<0.05);实验组不良反应发生情况低于常规组,差异有统计学意义(χ^(2)=4.883,P<0.05)。结论:DisCoVisc黏弹剂对白内障患者术后角膜水肿疗效确切,改善角膜内皮细胞和角膜水肿,降低不良反应发生率,预防效果明显。

Objective:To investigate the effectiveness of DisCoVisc viscoelastic agent in preventing postoperative corneal ede-ma in cataract patients.Methods:102 cases of cataract patients admitted to the hospital from March 2021 to March 2022 were se-lected as the study subjects,and were divided into the conventional group(51 cases)and the experimental group(51 cases)by ran-dom number table method.The conventional group received sodium hyaluronate treatment,and the experimental group received DisCoVisc viscoelastic treatment.Corneal endothelial cells,clinical efficacy,corneal edema,and adverse reactions before and after treatment were compared between the two groups.Results:After treatment,corneal endothelial cells were elevated in both groups,and the difference was statistically significant(t=3.855,P<0.05).Compared with the conventional group,the clinical efficacy of the experimental group was higher,and the difference was statistically significant(Z=5.254,P<0.05).Compared with 1 d postoperatively,corneal edema was reduced in both groups at 28 d postoperatively,and the difference was statistically significant(χ^(2)=5.258,P<0.05).The occurrence of adverse reactions in the experimental group was lower than that in the conventional group,and the difference was statistically significant(χ^(2)=4.883,P<0.05).Conclusion:DisCoVisc viscoelastic agent has proven efficacy in preventing postoperative corneal edema in cataract patients by improving corneal endothelial cells and corneal edema,and reducing the incidence of adverse effects.