原发性肾病综合征患者4C理念下的院内外护理研究

Study of In-hospital and Out-of-hospital Care of Patients with Primary Nephrotic Syndrome Under the 4C Concept

目的:分析4C理念下的院内-院外指导护理应用于原发性肾病综合征患者的护理效果。方法:选取2018年4月—2019年12月平顶山市第一人民医院肾病风混免疫科收治的88例原发性肾病综合征患者为研究对象,随机分为研究组(n=44)和对照组(n=44)。其中对照组落实常规性护理方案,研究组落实4C理念下的院内-院外指导护理方案。在干预前与干预后第3个月末,检测超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6);以焦虑自评量表(SAS)及抑郁症自评量表(SDS)对其消极情感状况展开评价;以生活质量量表(SF-36)对其生活质量展开评价。结果:干预后,研究组患者的hs-CRP、IL-6值均低于对照组,差异有统计学意义(t=12.147、15.587,P<0.05);研究组患者SAS、SDS评分均低于对照组,差异有统计学意义(t=14.857、12.147,P<0.05);研究组患者SF-36评分高于对照组,差异有统计学意义(t=10.743、9.987、8.527、9.879、11.368、13.258、14.789、13.254,P<0.05)。结论:4C理念下的院内-院外指导护理应用于原发性肾病综合征患者,能改善机体的炎性反应,且能缓解其内心的焦虑与抑郁情感,进而提高个体的生活质量。

Objective:To analyze the effect of in-hospital-out-of-hospital directed nursing care under the 4C concept applied to patients with primary nephrotic syndrome.Methods:88 patients with primary nephrotic syndrome admitted to the hospital from April 2018 to December 2019 were selected as study subjects and randomly divided into the study group(n=44)and control group(n=44).The control group implemented a routine nursing program,and the study group implemented an in-hospital-out-of-hospi-tal directed nursing program under the 4C concept.Ultrasensitive C-reactive protein(hs-CRP)and interleukin-6(IL-6)were mea-sured before the intervention and at the end of the 3rd month after the intervention.The Self-Assessment Scale for Anxiety(SAS)and Self-Assessment Scale for Depression(SDS)were used to evaluate negative affective status,and the Quality of Life Scale(SF-36)was used to evaluate quality of life.Results:After the intervention,the hs-CRP and IL-6 values of the patients in the study group were lower than those of the control group,and the difference was statistically significant(t=12.147,15.587,P<0.05).The SAS and SDS scores of the patients in the study group were lower than those of the control group,and the difference was statis-tically significant(t=14.857,12.147,P<0.05).The SF-36 scores of the patients in the study group were higher than those of the control group,and the difference was statistically significant(t=10.743,9.987,8.527,9.879,11.368,13.258,14.789,13.254,P<0.05).Conclusion:The 4C concept of in-hospital-out-of-hospital guided care applied to patients with primary nephrotic syn-drome improves the body’s inflammatory response,and relieves their internal anxiety and depression,so as to improve the in-dividual’s quality of life.