中药治疗肝硬化腹水合并自发性腹膜炎临床疗效观察

Clinical observation on the curative effect of traditional Chinese medicine on cirrhotic ascites combined with spontaneous peritonitis

目的:探讨中药治疗肝硬化腹水合并自发性腹膜炎的临床疗效。方法:选取符合标准的湿热水停型肝硬化腹水合并自发性腹膜炎患者80例为研究对象,随机分为2组,一组是对照组,另一组是试验组,每组各40例。对照组给予头孢克肟治疗,试验组在西医治疗的基础上给予自拟方剂。对2组病人的治疗有效率、治疗前后相关症状的变化、实验室指标的改善和中医症状积分进行了观察和对比。结果:试验组有效率(90.00%)与对照组有效率(77.50%)相比,有显著提高(P<0.05);试验组症状缓解所需时间更短(P<0.05);试验组各项实验室指标均好于对照组;前者中医症状积分低于后者。结论:中药治疗肝硬化腹水合并自发性腹膜炎有显著疗效,与单纯使用西医治疗相比,可显著改善患者的相关症状,减轻患者的疼痛,缩短患者病程,应该得到很好的推广。

Objective:To explore the clinical efficacy of traditional Chinese medicine in the treatment of cirrhosis and ascites combined with spontaneous peritonitis.Methods:80 patients with liver cirrhosis,ascites,and spontaneous peritonitis who met the criteria for hot and humid water treatment were selected as the research subjects,and were randomly divided into 2 groups,one group was the control group,and the other group was the experimental group,with 40 cases in each group.The control group was given cefixime treatment,and the experimental group was given self-made prescriptions on the basis of western medicine treatment.The treatment effectiveness,changes in related symptoms before and after treatment,improvements in laboratory indicators and TCM symptom scores were observed and compared between the two groups of patients.Results:Compared with the effective rate of the control group(77.50%),the effective rate of the experimental group(90.00%)was significantly improved(P<0.05);the time required for symptom relief in the experimental group was shorter(P<0.05);various items in the experimental group The laboratory indicators were all better than those of the control group;the TCM symptom scores of the former were lower than those of the latter.Conclusion:Traditional Chinese medicine has significant efficacy in treating liver cirrhosis and ascites combined with spontaneous peritonitis.Compared with western medicine treatment alone,it can significantly improve the patient’s related symptoms,reduce the patient’s pain,and shorten the patient’s course.It should be well promoted.