低剂量64排螺旋CT扫描对肺结节的诊断价值分析

Diagnostic value analysis of low-dose 64-slice spiral CT scan in pulmonary nodules

目的分析低剂量64排螺旋CT扫描在诊断肺结节上的临床价值。方法88例肺结节患者作为研究对象,均行低剂量64排螺旋CT扫描和常规剂量64排螺旋CT扫描检查。以穿刺活检病理结果为金标准,比较两种检查方法的CT扫描结果,对肺结节的诊断效能,有效辐射剂量和图像质量评分。结果穿刺活检结果显示,88例肺结节患者中恶性结节29例,良性结节59例;低剂量64排螺旋CT扫描检出恶性结节22例、占比75.86%(22/29),良性结节47例、占比79.66%(47/59);常规剂量64排螺旋CT扫描检出恶性结节23例、占比79.31%(23/29),良性结节49例、占比83.05%(49/59)。低剂量与常规剂量64排螺旋CT扫描的准确度、灵敏度、特异度、阳性预测值及阴性预测值比较,差异无统计学意义(P>0.05)。低剂量64排螺旋CT扫描的有效辐射剂量(7.55±1.21)mSv低于常规剂量64排螺旋CT扫描的(13.82±2.22)mSv,差异有统计学意义(P<0.05);两种检查方法图像质量评分比较差异无统计学意义(P>0.05)。结论与常规剂量64排螺旋CT扫描相比,低剂量64排螺旋CT扫描对肺结节的诊断准确度较高,诊断效能理想,图像质量相当,但低剂量64排螺旋CT扫描方案的辐射小,安全性更有保障,建议推广。

Objective To analyze the clinical value of low-dose 64-slice spiral CT scan in pulmonary nodules.Methods 88 patients with pulmonary nodules were selected as the study subjects,all of whom underwent low-dose 64-slice spiral CT scan and conventional-dose 64-slice spiral CT scan.Using the pathological results of puncture biopsy as the gold standard,the results of CT scan,diagnostic efficiency,effective radiation dose and image quality score of the two methods were compared.Results The results of puncture biopsy showed that there were 29 malignant nodules and 59 benign nodules in 88 pulmonary nodules.Low-dose 64-slice spiral CT scan detected 22 cases of malignant nodules,accounting for 75.86%(22/29),and 47 cases of benign nodules,accounting for 79.66%(47/59);conventional-dose 64-slice spiral CT scan detected 23 cases of malignant nodules,accounting for 79.31%(23/29),and 49 cases of benign nodules,accounting for 83.05%(49/59).There was no statistically significant difference in accuracy,sensitivity,specificity,positive predictive value,and negative predictive value between low-dose and conventional-dose 64-slice spiral CT scans(P>0.05).The effective radiation dose of low-dose 64 slice spiral CT scan was(7.55±1.21)mSv,which was lower than(13.82±2.22)mSv of conventional-dose 64-slice spiral CT scan,and the difference was statistically significant(P<0.05).The difference in image quality scores between the two methods was not statistically significant(P>0.05).Conclusion Compared with conventional-dose 64-slice spiral CT scan,low-dose 64-slice spiral CT scan has higher diagnostic accuracy,ideal diagnostic efficacy and comparable image quality for pulmonary nodules.However,low-dose 64-slice spiral CT scan has less radiation and more security,so it is recommended to be popularized.