急性心肌梗死患者经皮冠状动脉介入术后发生创伤后应激障碍的影响因素

Influencing factors of post-traumatic stress disorder in patients with acute myocardial infarction after percutaneous coronary intervention

目的:研究急性心肌梗死(AMI)患者经皮冠状动脉介入治疗(PCI)术后发生创伤后应激障碍(PTSD)的影响因素。方法:依据PTSD平民版量表(PCL-C)评分,于我院治疗的200例行PCI术的AMI患者被分为非PTSD组(144例,<44分)与PTSD组(56例,≥44分)。比较两组一般临床资料、事件相关反刍(反复思考)问卷表(ERRI)、艾森克人格问卷(EPQ)及社会支持评定量表(SSRS)评分,分析AMI患者PCI术后发生PTSD的影响因素。结果:200例行PCI的AMI患者中有56例(28.00%)发生PTSD。与非PTSD组比较,PTSD组年龄、高血压比例、ERRI量表侵入性反刍评分、EPQ量表神经质评分均显著升高,居住在城镇比例、ERRI量表主动反刍、内外向评分、SSRS评分均显著降低(P<0.05或<0.01)。多因素Logistic回归分析显示,年龄、SSRS评分是AMI患者PCI术后发生PTSD的独立保护因素(OR=0.885、0.602,P=0.024、0.035),侵入性反刍评分、神经质评分是其独立危险因素(OR=2.986、3.360,P=0.032、0.025)。结论:急性心肌梗死患者PCI术后PTSD的发生率较高。年龄、社会支持、神经质评分、侵入性反刍评分等是急性心肌梗死患者PCI术后发生PTSD的影响因素。

Objective:To study influencing factors of post-traumatic stress disorder(PTSD)in patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI).Methods:According to score of PTSD checklist-civilian version(PCL-C),a total of 200 AMI patients undergoing PCI in our hospital were divided into non-PTSD group(n=144,<44 scores)and PTSD group(n=56,≥44 scores).General clinical data,scores of event related rumination inventory(ERRI),Eysenck personality questionnaire(EPQ)and social support rating scale(SSRS)were compared between two groups.Influencing factors of PTSD in AMI patients after PCI were analyzed.Results:There were 56 cases(28.00%)developing PTSD among the 200 AMI patients undergoing PCI.Compared with non-PTSD group,there were significant rise in age,percentage of hypertension,scores of invasive rumination of ERRI and neuroticism of EPQ,and significant reductions in percentage of living in town,scores of active rumination and internal&external of ERRI and SSRS in PTSD group(P<0.05 or<0.01).Multivariate Logistic regression analysis indicated that age and score of SSRS were independent protective factors for PTSD in AMI patients after PCI(OR=0.885,0.602,P=0.024,0.035),and scores of invasive rumination and neuroticism were independent risk factors for it(OR=2.986,3.360,P=0.032,0.025).Conclusion:Incidence rate of PTSD is higher in patients with acute myocardial infarction after PCI.Age,social support,scores of neuroticism and invasive rumination were influencing factors of PTSD in patients with acute myocardial infarction after PCI.