双源CT联合血清CRP水平检测对痛风性关节炎的诊断价值

Analysis of diagnostic value of CT combined with serum CRP level in gouty arthritis

目的 探讨双源CT联合血清C反应蛋白(CRP)水平检测对痛风性关节炎的诊断价值。方法 选择本院2018年1月—2022年3月收治的166例疑似痛风性关节炎患者,分为痛风性关节炎组与非痛风性关节炎组行双源CT及血清CRP水平检测,以美国风湿病协会(ACR)制定的痛风性关节炎诊断标准明确痛风性关节炎诊断,计算双源CT及血清CRP单独与联合诊断痛风性关节炎的效能并分析其临床价值。结果 共有126例患者(75.90%)明确痛风性关节炎诊断。痛风性关节炎组双源CT图像绿色结晶检出率高于非痛风性关节炎组,差异有统计学意义(P<0.05)。痛风性关节炎组血清CRP水平高于非痛风性关节炎组(P<0.05),但两组血清CRP阳性率比较,差异无统计学意义(P>0.05)。双源CT联合血清CRP诊断痛风性关节炎的特异性、准确率、阳性预测值、阴性预测值均高于单项诊断,差异有统计学意义(P<0.05)。结论 双源CT联合血清CRP水平检测能够为痛风性关节炎的无创诊断提供可靠参考。

Objective To analyze the diagnostic value of Dual source CT combined with serum C-reactive protein(CRP) level in gouty arthritis.Methods 166 patients with suspected gouty arthritis admitted to our hospital from January 2018 to March 2022 were examined by Dual source CT and serum CRP levels.The diagnosis of gouty arthritis was confirmed by the diagnostic criteria of gouty arthritis established by American Rheumatology Association(ACR).The diagnostic efficacy of Dual source CT and serum CRP alone and jointly in gouty arthritis was calculated and its clinical value was analyzed.Results Of the 166 patients,126(75.90%) had a definite diagnosis of gouty arthritis.The detection rate of green crystals in Dual source CT images in gouty arthritis group was higher than that in non-gouty arthritis group,and the difference was statistically significant(P<0.05).Serum CRP level in gouty arthritis group was higher than that in non-gouty arthritis group(P<0.05),but there was no statistical difference between the two groups in serum CRP positive rate(P>0.05).The specificity,accuracy,positive predictive value and negative predictive value of CT combined with serum CRP in the diagnosis of gouty arthritis are higher than those of single diagnosis,and the difference was statistically significant(P<0.05).Conclusion Dual source CT combined with serum CRP level can provide reliable reference for noninvasive diagnosis of gouty arthritis.