中医健脾养胃法在胃癌治疗中的应用探讨

Application of Traditional Chinese Medicine spleen strengthening and stomach nourishing method in the treatment of gastric cancer

目的分析常规化疗治疗期间联合中医健脾养胃法在胃癌患者治疗中的使用效果。方法此次试验选取研究对象50例,均为淄博市中医医院2020年4月-2023年3月期间接收并予以治疗的胃癌患者,依据治疗期间所用方案不同划分为对照组和观察组,两组中均有25例患者计入,实际治疗为常规化疗、中医健脾养胃法联合治疗。获取两组患者治疗前后证候积分、肿瘤标志物水平、生存质量评分,实施对比分析。结果治疗前两组主症积分及次症积分比较,差异无统计学意义(P>0.05);治疗后观察组主症积分(5.14±2.31)分、次症积分(10.02±3.14)分,均低于对照组的(8.08±3.17)分、(14.58±2.02)分,组间差异有统计学意义(P<0.05)。治疗前两组肿瘤标志物水平比较,差异无统计学意义(P>0.05);治疗后癌胚抗原、血清糖链抗原125、血清糖链抗原50三项肿瘤标志物水平值均降低,组内对比,结果显示差异有统计学意义(P<0.05),但组间对比,差异无统计学意义(P>0.05)。治疗前两组生存质量评分比较,差异无统计学意义(P>0.05);治疗后观察组躯体功能、角色功能、情绪功能、认知功能各项评分分别为(86.56±1.02)分、(87.65±1.08)分、(88.69±2.46)分、(85.65±2.19)分,高于对照组的(79.58±2.06)分、(80.16±1.28)分、(81.06±2.66)分、(76.81±1.26)分,组间差异有统计学意义(P<0.05)。结论中医健脾养胃法在胃癌患者治疗中的联合使用效果较为突出,可以加快患者机体各项证候的改善速度,调节患者机体中肿瘤标志物的水平,提高患者生存质量。

Objective To analyze the effectiveness of combining Traditional Chinese Medicine spleen strengthening and stomach nourishing therapy with conventional chemotherapy in the treatment of gastric cancer patients.Method This experiment selected 50 gastric cancer patients who were received and treated in our hospital from April 2020 to March 2023.They were divided into a control group and an observation group based on the different treatment regimens used during the treatment period.25 patients were included in both groups,and the actual treatment was a combination of conventional chemotherapy and Traditional Chinese Medicine spleen nourishing stomach method.Obtain symptom scores,tumor marker levels,and quality of life of two groups of patients before and after treatment,and conduct comparative analysis.Result Before treatment,there was no statistically significant difference in the total score of the main symptom and the total score of the secondary symptom between the two groups(P>0.05);after treatment,the main symptom score(5.14±2.31)and secondary symptom score(10.02±3.14)of the observation group were lower than those of the control group(8.08±3.17)and(14.58±2.02),with statistically significant differences between the groups(P<0.05).There was no statistically significant difference in the levels of tumor markers between the two groups before treatment(P>0.05);after treatment,the levels of tumor markers including carcinoembryonic antigen,serum sugar chain antigen 125,and serum sugar chain antigen 50 all decreased.The intra group comparison results showed statistically significant differences(P<0.05),but the inter group comparison differences were not statistically significant(P>0.05).There was no statistically significant difference in the quality of life scores between the two groups before treatment(P>0.05);after treatment,the scores of physical function,role function,emotional function,and cognitive function in the observation group were(86.56±1.02)points,(87.65±1.08)points,(88.69±2.46)points,and(85.65±2.19)points,respectively,higher than those in the control group(79.58±2.06)points,(80.16±1.28)points,(81.06±2.66)points,and(76.81±1.26)points,with statistically significant differences between the groups(P<0.05).Conclusion The combined use of the Traditional Chinese Medicine spleen strengthening and stomach nourishing method in the treatment of gastric cancer patients has a prominent effect,which can accelerate the improvement of various symptoms in the patient's body,regulate the level of tumor markers in the patient's body,and improve the patient's quality of life.