甘肃省某三甲中医院多重耐药菌感染分布情况探究

Exploration of the Distribution of Multidrug-Resistant Bacterial Infections in a Tertiary Traditional Chinese Medicine Hospital in Gansu Province

目的探究甘肃省某三甲中医院多重耐药菌感染分布情况。方法选取甘肃省某三甲中医院2019年—2022年多重耐药菌临床检测结果,利用“医院感染和传染病实时监控平台”对多重耐药菌(MDRO)检出率、重点监测MDRO分布构成、感染科室及感染标本来源分布进行回顾性分析。结果2019年—2022年剔除重复样本后共收集1360例MDRO阳性病例,重点监测MDRO分布排序依次为耐碳青霉烯类抗菌药物鲍曼不动杆菌(CR-AB)、耐甲氧西林金黄色葡萄球菌(MRSA)、耐碳青霉烯类抗菌药物铜绿假单胞菌(CR-PA)、耐碳青霉烯类抗菌药物肠杆菌科细菌(CRE)、耐万古霉素肠球菌(VRE),其中CR-AB的检出率呈下降趋势;重点监测MDRO感染科室分布广泛,其中以重症医学科、骨髓炎科、肺病科、脑病科感染为主,分别为34.71%、10.51%、7.79%、6.47%;临床送检实验标本以痰液和伤口分泌物为主,分别为45.00%、26.62%。结论甘肃省某三甲中医院MDRO感染的发生率近年来依旧在逐步增加,还需进一步加强相关感染防控工作落实。

Objective Explore the distribution of multidrug-resistant bacterial infections in a tertiary traditional Chinese medicine hospital in Gansu Province.Methods The clinical test results of multidrug-resistant bacteria from a tertiary traditional Chinese medicine hospital in Gansu Province from 2019 to 2022 were selected,used the"Hospital Infection and Infectious Disease Real Time Monitoring Platform"to retrospectively analyze the MDRO detection rate,key monitoring MDRO distribution composition,infection departments,and source distribution of infection samples.Results A total of 1360 MDRO positive cases were collected after eliminating duplicate samples from 2019 to 2022.The distribution of MDRO under key monitoring was in the order of carbapenem resistant Acinetobacter baumannii(CR-AB),methicillin resistant Staphylococcus aureus(MRSA),carbapenem resistant Pseudomonas aeruginosa(CR-PA),carbapenem resistant Enterobacteriaceae(CRE),vancomycin resistant Enterococcus(VRE),the detection rate of CR-AB showed a decreasing trend;The key monitoring departments for MDRO infection were widely distributed,with infection rates mainly in the departments of Intensive Care Medicine,Osteomyelitis,Pulmonary Disease and Encephalopathy,accounted for 34.71%,10.51%,7.79%and 6.47%.The clinical test specimens were mainly composed of sputum and wound secretions,accounted for 45.00%and 26.62%.Conclusion The infection of multidrug-resistant bacteria in this hospital has been on the rise in recent years,and further strengthening of relevant infection prevention and control work is needed.