AMI患者经皮冠状动脉介入治疗预后风险评分系统的研究进展

Research Progress in Prognostic Risk Scoring System for Patients with AMI after PCI

急性心肌梗死(AMI)是冠状动脉疾病最为严重的临床表现,主要治疗方法是经皮冠状动脉介入治疗(PCI),部分患者术后仍预后不良。影响预后的因素主要包括伴随疾病、血液检验以及手术治疗方式的选择等。构建简便实用的风险评分是当前AMI治疗的关键。目前AMI相关的风险评分主要分为三类:传统经典评分(TIMI、GRACE等),出血评分(CRUSADE、ACUITY等)和PCI术后评分(Mayo Clinic PCI、CAMI等),这些评分各有优势,但仍有不足,如传统经典评分虽体系完整且应用广泛,但缺乏PCI相关信息,在预后预测上表现并不佳。因此,未来的AMI研究应更加关注创新指标的纳入及模型应用。

Acute myocardial infarction(AMI)is the most serious clinical manifestation of coronary artery disease.Although percutaneous coronary intervention(PCI)is the main treatment for AMI,some patients still have poor prognosis after operation.There are many factors affecting the prognosis of AMI,including concomitant diseases,blood tests and surgical procedures.Constructing a simple and practical risk scoring system has become a key issue for the treatment of AMI.At present,the risk scores related to AMI are mainly divided into three categories:classic scores(TIMI,GRACE,etc.),bleeding scores(CRUSADE,ACUITY,etc.),and post-PCI scores(Mayo Clinic PCI,CAMI,etc.).These scores have their own advantages and shortcomings.For example,although the classic scoring system is complete and widely used,it lacks PCI-related information and does not perform well in prognosis prediction.Therefore,the future study on AMI should pay more attention to incorporation of innovative indicators and model application.