颅脑超声检测大脑中动脉、豆纹动脉血流参数在评估缺氧缺血性脑病新生儿病情中的应用价值

The value of cranial ultrasound in detecting blood flow parameters of the middle cerebral artery and the douglas artery in assessing the condition of neonates with hypoxic-ischemic encephalopathy

目的:探究颅脑超声检测大脑中动脉、豆纹动脉血流参数在评估缺氧缺血性脑病新生儿病情中的应用价值。方法:分别从2021年3月至2023年5月在本院确诊的缺氧缺血性脑病新生儿和健康新生儿中各抽取60例作为本研究对象,并分别命名为病例组和对照组,两组出生后24h、48h及72h均接受颅脑超声检测,获取大脑中动脉、豆纹动脉血流参数,并将病例组按照病情严重程度分为轻度组、中度组和重度组,应用ROC曲线分析大脑中动脉、豆纹动脉血流参数对缺氧缺血性脑病和评估缺氧缺血性脑病病情严重度的诊断效能。结果:病例组出生后24h、48h及72h大脑中动脉和豆纹动脉的收缩期血流峰值速度和舒张末期血流速度低于对照组,阻力指数高于对照组(P<0.05);病例组不同病情严重度患儿出生后24h、48h及72h大脑中动脉和豆纹动脉的收缩期血流峰值速度、舒张末期血流速度和阻力指数组间差异具有统计学意义(P<0.05);ROC曲线分析发现,大脑中动脉和豆纹动脉的血流参数诊断缺氧缺血性脑病和评估缺氧缺血性脑病病情严重度的效能良好(P<0.05)。结论:颅脑超声检测大脑中动脉、豆纹动脉血流参数在新生儿缺氧缺血性脑病诊断和病情严重度评估中具有良好的诊断效能,可作为评估新生儿神经行为发育异常的依据。

Objective:Investigating the value of cranial ultrasound in detecting blood flow parameters of the middle cerebral artery and the douglas artery in assessing the condition of neonates with hypoxic-ischemic encephalopathy.Methods:Sixty cases each were taken from the newborns with hypoxic-ischemic encephalopathy diagnosed and healthy newborns delivered in our hospital from March 2021 to May 2023 as the subjects of this study,respectively,and were named as the case group and the control group,respectively,and the two groups were subjected to cranial ultrasonography to obtain the blood flow parameters of the middle cerebral artery and the doudoune arteries at 24 h,48 h,and 72 h after birth.The case group was divided into mild group,moderate group,and severe group according to the seriousness of the disease,and the effectiveness of using ROC curve analysis to diagnose hypoxic-ischemic encephalopathy and evaluate the severity of hypoxic-ischemic encephalopathy by analyzing blood flow parameters of the middle cerebral artery and lenticular artery.Results:The Vs and Vd of the middle cerebral artery and the bean-stripe artery at 24 h,48 h and 72 h after birth were slower in the case group than in the control group,and the RI than in the control group(P<0.05).The differences in Vs,Vd and RI of the middle cerebral artery and arterioles at 24 h,48 h and 72 h after birth were statistically significant in the case group with different severity of the disease(P<0.05).The ROC curve analysis showed that the blood flow parameters of the middle cerebral artery and arterioles were effective in the diagnosis of hypoxic ischemic encephalopathy and in the assessment of the severity of hypoxic ischemic encephalopathy(P<0.05).Conclusion:Craniocerebral ultrasound detection of blood flow parameters of middle cerebral artery and lentistriate artery has good diagnostic efficacy in the diagnosis and severity assessment of neonatal hypoxic-ischemic encephalopathy,and can be used as a basis for the evaluation of neonatal neurobehavioral developmental abnormalities.