内镜下圈套器冷切除术对结直肠小息肉患者息肉完整切除率及应激反应的影响

Impacts of endoscopic cold snare polypectomy on the complete polypectomy rate and stress response in patients with small colorectal polyps

目的探讨内镜下圈套器冷切除术(CSP)对结直肠小息肉患者息肉完整切除率及应激反应的影响。方法选取结直肠小息肉患者138例为研究对象,按照单盲随机分组法分为对照组(n=69)和观察组(n=69)。对照组行内镜下圈套器热切除术(HSP),观察组行CSP。比较2组患者息肉切除时间、手术时间、住院时间、完整切除率以及肾上腺素(E)、去甲肾上腺素(NE)、皮质醇(Cor)、C反应蛋白(CRP)、白细胞介素-6(IL-6)水平,术后6个月时息肉新生率与息肉复发率。结果观察组息肉切除时间、手术时间、住院时间均短于对照组,差异有统计学意义(P<0.05);2组术后E、NE、Cor、CRP和IL-6水平均较术前升高,但观察组低于对照组,差异有统计学意义(P<0.05)。结论CSP与HSP治疗结直肠小息肉患者的完整切除率相近,但CSP的应激反应和炎症反应更轻,更有利于患者恢复。

Objective To investigate the effect of endoscopic cold snare polypectomy(CSP)on the complete polyp resection rate and stress response in patients with colorectal small polyps.Methods A total of 138 patients with colorectal small polyps were selected,and were assigned to control group(n=69)and observation group(n=69)according to single-blind randomization method.The control group underwent endoscopic hot snare polypectomy(HSP),and the observation group underwent CSP.The polypectomy time,surgical duration,hospital stay,complete resection rate,the levels of epinephrine(E),norepinephrine(NE),cortisol(Cor),C-reactive protein(CRP),interleukin-6(IL-6),the 6-month polyp regeneration rate and polyp recurrence rate after operation were compared between the two groups.Results The polyp resection time,operation duration,and hospital stay in the observation group lower than those in the control group(P<0.05);the levels of E,NE,Cor,CRP and IL-6 in two groups were higher after surgery,and the observation group was lower than the control group(P<0.05).Conclusion CSP has a similar complete resection rate to endoscopic HSP in patients with colorectal small polyps,but CSP has less stress and inflammation and is more conducive to recovery.