DWI、DCE-MRI在中老年宫颈癌诊断、分期中的价值

The Value of DWI and DCE-MRI in the Diagnosis and Staging of Cervical Cancer in Middle-aged and Elderly People

目的探讨弥散加权序列(DWI)及动态增强磁共振成像(DCE-MRI)在宫颈癌诊断、分期中的价值。方法选取经病理证实的宫颈癌患者47例,行常规MR、扩散加权成像(DWI)扫描和动态对比增强磁共振(DCE-MR)扫描。按照FIGO分期分为两组,由两名有经验的影像医师勾画ROI,比较Ⅰ期+ⅡA期组与ⅡB及以上分期组组间不同定量参数之间的差异。结果1组平均ADC值为(0.869±0.181)×10^(-3)mm^(2)/s,2组为(0.716±0.1)×10^(-3)mm^(2)/s,差异有统计学意义(P<0.05)。1、2组K^(trans)、K_(ep)、V_(e)非参数检验结果示差异有统计学意义(P<0.05)。结论在常规MRI扫描基础上,应用DWI及DCE-MRI可以更全面、准确地对宫颈癌进行诊断和分期评估,对临床制定个性化的治疗方案具有重要的参考价值。

Objective To investigate the value of diffusion weighted imaging(DWI)and dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)in the diagnosis and staging of cervical cancer.Methods A total of forty-seven patients with cervical cancer confirmed by pathology were enrolled and subjected to routine MR,diffusion weighted imaging(DWI),and dynamic contrast-enhanced magnetic resonance(DCE-MR)scanning.By FIGO staging,they were split into two groups,stageⅠ+ⅡA group and the stageⅡB+Ⅲ+Ⅳgroup,and ROIs were drawn by two experienced radiologists to compare the differences of different quantitative parameters between the two groups.Results The variance±standard deviation of ADC value was(0.869±0.181)×10^(-3)mm^(2)/s in group 1,while in group 2 it was(0.716±0.1)×10^(-3)mm^(2)/s,which was statistically significant.The results of nonparametric tests of K_(trans),K_(ep) and V_(e) in group 1and group 2 showed statistically significant differences(p<0.05).Conclusion On the basis of conventional MRI scanning,the application of DWI and DCE-MRI can provide more comprehensive and accurate diagnosis,measurement and the staging of tumor assessment in cervical cancer,which has important reference value for the development of personalized treatment plans in clinical practice.