影像组学预测肝细胞癌微血管侵犯的研究现状

Research Status of Radiomics for Predicting Microvascular Invasion in Hepatocellular Carcinoma

肝细胞癌(HCC)是目前对人类健康造成巨大威胁的常见恶性肿瘤之一,由于其发病率、死亡率都很高以及预后不理想,对于肝细胞癌的治疗一直都是我们需要攻克的难题。微血管侵犯(MVI)已经被多项研究证实是肝细胞癌术后复发以及预后不良的重要原因。然而,MVI的诊断主要是在术后通过肝细胞癌的病理学检查来确诊。如果能在术前对MVI进行一定的预测,将会对指导个体化治疗方案以及提高患者的预后产生巨大的影响。现阶段已有不少的研究利用CT或MRI影像组学的方法对HCC MVI进行预测,并且都取得了很好的效果。本文将对目前关于HCC MVI影像组学预测的研究进展进行阐述。

Hepatocellular carcinoma(HCC)is one of the most common malignant tumors that pose a great threat to human health,and its treatment has always been a challenge due to its high morbidity and mortality rates and poor prognosis.Microvascular invasion(MVI)has been shown to be an important cause of postoperative recurrence and poor prognosis in hepatocellular carcinoma in several studies.However,the diagnosis of MVI is mainly confirmed by histopathologic examination of hepatocellular carcinoma after surgery.If MVI could be predicted before surgery,it would have a great impact on guiding individualized treatment plans and improving patients'prognosis.At this stage,many studies have been conducted on the prediction of HCC MVI using CT or MRI radiomics,and all of them have achieved very good results.In this paper,we will describe the current research progress on the radiomic prediction of HCC MVI.