单纯鞍下恶性颅咽管瘤一例报告及文献回顾

Entire Infrasellar Malignant Craniopharyngioma:A Case Report and Literature Review

本文报道单纯位于鞍下恶性颅咽管瘤1例。患者男性,60岁,因2月前无明显诱因出现头痛入院。CT表现为鞍下区等密度软组织肿块,颅底斜坡骨质破坏。MR表现为鞍下区不规则实性肿块,T_(1)WI呈均匀低信号,T_(2)WI呈稍高信号,DWI呈均匀低信号,T_(2)WI和T_(1)WI增强序列均表现为高低相间混杂信号的“椒盐征”。术后见鞍内垂体结构完整,鞍上及鞍内未侵犯。最终病理诊断为恶性颅咽管瘤(鳞形细胞癌)。

This paper reports a case of malignant craniopharyngioma simply located under the sella turcica.The patient,male,60 years old,was admitted to the hospital for headache without obvious inducement 2 months ago.CT findings were isodense soft tissue mass in the infrasellar region and bone destruction in the clivus of the skull base.MR imaging showed irregular solid mass in the infrasellar region.On T_(1)WI,the signal was uniform and low.On T_(2)WI,the signal was slightly high,and on DWI,the signal was uniform and low.Both T_(2)WI and T_(1)WI enhanced sequence showed"salt and pepper sign"with high and low mixed signals.Postoperatively,the intrasellar pituitary structure was intact,and there was no invasion in the suprasellar and intrasellar regions.The final pathological diagnosis was malignant craniopharyngioma(squamous cell carcinoma).