白头翁汤对溃疡性结肠炎肠黏膜屏障作用机制

Mechanism of Bai Tou Weng decoction on the intestinal mucosal barrier of ulcerative colitis

近年来溃疡性结肠炎临床发病率不断上升,现代医学对其治疗手段较为局限,并且存在较大的不良反应,疗效难以维持等诸多问题。中医学以其特有的理论体系和治疗模式在治疗本病时具有独特优势,可以有效改变现代医学的治疗困境。白头翁汤作为中医典籍名方,对溃疡性结肠炎的临床治疗效果显著。在临床上广泛运用于溃疡性结肠炎的治疗,然而关于其具体治疗机制尚无定论。系统论述白头翁汤对溃疡性结肠炎肠黏膜屏障作用机制有利于指导临床诊疗工作。

In recent years,the clinical incidence of ulcerative colitis has been growing.Yet modern medicine has limited treatment methods for the disease,and there are many problems such as severe side effects and difficult to maintain the efficacy,etc.With its unique theoretical system and treatment mode,Chinese medicine possesses its unique advantages in treating this disease,which can effectively alter the treatment dilemma faced by modern medicine.As a famous prescription in Chinese medicine,the Bai Tou Weng decoction can achieve a remarkable efficacy in the clinical treatment of ulcerative colitis.Though widely used in the clinical treatment of ulcerative colitis,its specific treatment mechanism is still inconclusive.Therefore,a systematic discussion of the mechanisms of Bai Tou Weng decoction on the intestinal mucosal barrier of ulcerative colitis is conducive to better guiding its clinical diagnosis and treatment.