浅议分子编辑——原子尺度上的积木游戏

A Brief Discussion of Molecular Editing Technology:The Building Block Game on Atomic Scale

随着近年来有机合成化学的发展,分子编辑技术在有机合成与逆合成分析中逐渐展现出巨大的优势,并且在药物分子的修饰和结构优化中有着极为重要的作用。本文介绍了分子编辑技术的具体内容,其中包括有机合成中用于骨架调整和外围修饰的反应,如骨架跃迁和C―H官能化,并在最后对分子编辑技术的未来前景进行了展望。

With the organic synthetic chemistry developed in recent years,molecular editing technology has gradually demonstrated significant advantages in both synthetic chemistry and retrosynthetic analysis and plays an important part in the decoration and the optimization of drugs.We introduce some of the reactions about molecular editing,such as skeletal rearrangement and C―H functionalization,and the prospect of molecular editing in the future is discussed in the final part.