半夏厚朴汤加减联合葛根芩连汤治疗慢性咽喉炎的临床效果分析

Clinical effect of banxia HOUPU decoction combined with gegen qinlian decoction on chronic pharyngitis

目的研究慢性咽喉炎患者行半夏厚朴汤加减+葛根芩连汤治疗的效果。方法选择本院2020年9-2022年9月收治的80例慢性咽喉炎患者,“双盲法”分单一组(葛根芩连汤,n=40)、科研组(葛根芩连汤+半夏厚朴汤加减,n=40),两组疗效比较。结果用药前比较中医证候积分、炎症因子无差异,用药后比较不良反应也无差异,P>0.05;用药后较单一组,科研组中医证候积分更低;IL-6、TNF-α及hs-CRP值更低,IL-2值更高;科研组有效率(5.00%)高于单一组(7.50%),χ^(2)=4.114;p=0.043,P<0.05。结论半夏厚朴汤+葛根芩连汤治疗慢性咽喉炎可减轻症状、炎症程度,增强疗效、保证用药安全,值得推崇。

Objective To study the effect of banxia HOUPU decoction plus gegen qinlian decoction on patients with chronic pharyngitis.Methods From September 2020 to September 2022,80 patients with chronic pharyngitis were selected,the double-blind method was applied to the control group(Pueraria Montana Qinlian decoction,N=40)and the observation group(gegen Qinlian decoction plus Banxia houpu decoction,N=40).Results There was no difference in TCM syndrome score and inflammatory factors before and after treatment,and there was no difference in adverse reaction after treatment,P>0.05.Compared with the control group,the TCM syndrome score was lower in the Observation Group The levels of IL-6,TNF-αand hs-CRP were lower and the levels of IL-2 were higher in the Observation Group(5.00%)than in the control group(7.50%),χ^(2)=4.114;P=0.043,P<0.05;.Conclusion Banxia Houpu decoction and gegen qinlian decoction can reduce the symptoms and inflammatory degree of chronic laryngitis,enhance the efficacy and ensure the safety of medication,which is worthy of praise.