帕金森病患者伴发抑郁非药物管理的最佳证据总结

Summary of the best evidence for non-pharmacological management of Parkinson's disease patients with depression

目的检索、筛选及总结帕金森病患者伴发抑郁非药物管理的最佳证据,为临床医护人员对帕金森病患者伴发抑郁开展规范化非药物管理提供循证依据。方法遵循"6S"证据模型,自上而下系统检索UpToDate、BMJ、澳大利亚乔安娜布格斯研究所循证卫生保健中心数据库、英国国家卫生与临床优化研究所、国际指南网、美国国立指南库、苏格兰学院间指南网、医脉通、加拿大帕金森病协会、Cochrane Library、CINAHL、PubMed、Web of Science、Embase、中国生物医学文献数据库、中国知网、万方数据库中相关文献,检索时限为建库至2023年3月31日。依据文献标准进行方法学质量评价后,对符合标准的文献进行证据提取和汇总,并对各项证据进行等级判定。结果共纳入22篇文献,其中临床决策1篇、指南3篇、系统评价14篇和专家共识4篇,围绕筛查与评估、心理干预、物理治疗、中医理疗、运动锻炼、健康教育6个方面形成30条最佳证据。结论该研究总结了帕金森病患者伴发抑郁非药物管理的最佳证据,为临床制定帕金森病患者伴发抑郁非药物管理方案提供循证依据。

Objective To retrieve,screen,and summarize the best evidence for non-pharmacological management of Parkinson's disease patients with depression,so as to provide evidence-based basis for medical and nursing staff to standardize the non-pharmacological management.Methods Following the"6S"evidence model,relevant literature was systematically searched from top to bottom in UpToDate,British Medical Journal,Joanna Briggs Institute Evidence-Based Health Care Center Database,National Institute for Health and Clinical Excellence,Guidelines International Network,Agency for Healthcare Research and Quality,Scottish Intercollegiate Guidelines Network,Medlive,Parkinson's Society of Canada,Cochrane Library,CINAHL,PubMed,Web of Science,Embase,China Biology Medicine,China National Knowledge Infrastructure,and WanFang Data.The search period was from database establishment to March 31,2023.After conducting methodological quality evaluation based on literature standards,evidence was extracted and summarized from literature that met the standards,and the level of each evidence was determined.Results A total of 22 articles were included,including one clinical decision-making,three guidelines,14 systematic reviews,and four expert consensuses.A total of 30 best evidence were formed from six aspects,namely screening and evaluation,psychological intervention,physical therapy,traditional Chinese medicine therapy,exercise,and health education.Conclusions The best evidence for non-pharmacological management of Parkinson's disease patients with depression summarized provides evidence-based basis for the development of non-pharmacological management plans for Parkinson's disease patients with depression.