摘要
Suffering from various pathological risks in daily life,such as cariogenic bacteria,traumatic force,and extreme pH values,tooth enamel defect has a stunning global prevalence of over 85%.Even worse,the enamel defect in most vertebrates cannot be self-regenerated to restore both exquisite hierarchical structures and exceptional mechanical properties throughout their lifetime[1].As such,a series of esthetic and functional complications caused by enamel defects exist persistently,such as dysfunction of the oral and maxillofacial system,reduced chewing efficiency,dentine hypersensitivity,periodontitis,etc.Reliable and sustainable enamel repair techniques are urgently needed to improve life quality and ease the financial burden[2].
作者
邓菁菁
于唯一
卫彦
邓旭亮
Jingjing Deng;Weiyi Yu;Yan Wei;Xuliang Deng(Beijing Laboratory of Biomedical Materials,Department of Geriatric Dentistry,Peking University School and Hospital of Stomatology,Beijing 100081,China)
基金
the National Key R&D Program of China(2020YFA0710401 and 2022YFB3804300)
the National Natural Science Foundation of China(82221003,82225012,82071161
U22A20160)
the Beijing Municipal Science&Technology Commission(221100007422088)。
