肠动力障碍13例分析

Analysis of 13 cases of enteric dysmotility

目的分析肠动力障碍(ED)的临床特点,以提高临床诊治能力。方法回顾性分析上海交通大学医学院附属第九人民医院和南京医科大学第四附属医院2019年8月至2022年7月13例行小肠测压的ED患者临床资料,包括临床表现、小肠压力测定结果、治疗和预后。结果13例患者中,小肠压力测定结果1项异常9例,2项异常2例,3项异常2例。患者均有便秘病史,5例以便秘起病行结肠次全切除术。3例患者伴有严重腹痛,其中1例依赖阿片类药物。8例患者采用手术治疗,均获得营养学改善及症状减轻。结论ED是明确定义的疾病,具有清晰的诊断标准,部分患者外科治疗可以改善症状。

Objective To investigate the clinical characters of enteric dysmotility(ED),in order to improve clinical diagnosis and treatment capabilities.Methods The clinical data of 13 ED patients underwent small intestinal manometry from August 2019 to July 2022 in the Shanghai Jiaotong University Affiliated Ninth People's Hospital and the Fourth Affiliated Hospital of Nanjing Medical University were retrospectively analyzed,including the clinical manifestation,small intestinal manometry result,treatment and prognosis.Results Among 13 patients,1 abnormality was presented in 9 cases,2 abnormalities presented in 2 cases and 3 abnormalities presented in 2 cases.All 13 cases presented a history of constipation,5 cases started with constipation and underwent subtotal colectomy.Three patients showed severe chronic abdominal pain with one of them opiate dependence.Eight patients underwent surgical treatment,all of which achieved nutritional improvement and symptom relief.Conclusions ED is a concisely defined disease with clear diagnostic criteria.The surgery can increase the symptoms of some patients.