改良青龙摆尾针刺法治疗带状疱疹后遗神经痛疗效研究

Therapeutic Effect of Modified Qinglong Swinging Tail Acupuncture in Treatment of PHN

目的:观察改良青龙摆尾针刺法治疗带状疱疹后遗神经痛疗效。方法:将本院收治的91例带状疱疹后遗神经痛患者(2020年2月—2022年6月)纳入研究,以随机数字表法将纳入患者分为针刺组(46例)与常规组(45例),常规组患者采取常规疗法(甲钴胺+维生素+吲哚美辛肠溶片)治疗,针刺组治疗方法在常规组基础上结合改良青龙摆尾针刺法治疗,比较治疗效果、治疗前后患者中医证候积分变化、血清炎症因子水平变化及疼痛评分(VAS)变化与睡眠质量(PSQI)评分变化、皮肤病生活质量评估量表(DLQI)评分变化、不良反应和6个月疾病复发率。结果:针刺组患者与常规组治疗总有效率分别为95.65%(44/46)、82.22%(37/45),针刺组更高,差异具有统计学意义(P<0.05);两组患者治疗前中医证候积分、白介素-6(IL-6)及C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)等血清炎症因子水平、VAS评分、PSQI评分和DLQI评分比较,差异无统计学意义(P>0.05),治疗后各组患者中医证候积分、血清炎症因子水平(IL-6、CRP及TNF-α)、VAS评分、PSQI评分和DLQI评分均改善,针刺组患者治疗后各指标均优于常规组,差异具有统计学意义(P<0.05);针刺组患者不良反应率为4.35%(2/45),与常规组的4.44%(2/46)比较,差异无统计学意义(P>0.05);针刺组患者6个月内疾病复发率为0.00%(0/46)低于常规组的8.89%(4/45),差异具有统计学意义(P<0.05)。结论:带状疱疹后遗神经痛患者采取改良青龙摆尾针刺法治疗甚佳,患者症状明显改善,疼痛缓解,睡眠与生活质量佳,不良反应较少,且6个月内疾病复发率较低,值得应用。

Objective:To observe the effect of modified Qinglong swinging tail acupuncture in treatment of postherpetic neuralgia(PHN).Methods:A total of 91 patients with PHN were randomly divided into the acupuncture group(n=46)and the conventional group(n=45).The conventional group was treated with conventional therapy(mecobalamine,vitamin and indomethacin enteric-covered tablets);on which basis,the acupuncture group was also treated with modified Qinglong wagging tail acupuncture.Therapeutic effect,changes of TCM sydrom scores,serum inflammatory factors,VAS score,PSQI score and DLQI score,as well as adverse reactions and disease recurrence rate within 6 months were compared between the two groups.Results:The total effective rate of the acupuncture group was 95.65%(44/46),which was higher than 82.22%(37/45)of the conventional group(P<0.05).There were no statistical differences in TCM sympot scores,levels of serum inflammatory factors,including interleukin-6(IL-6),C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),VAS score,PSQI score and DLQI score between the two groups before the treatment(P>0.05);the above indexes were all improved after the treatment in the two groups,and the improvements were more significant in the acupuncture group than those in the conventional group(P<0.05).The adverse reaction rate was 4.35%(2/45)in the acupuncture group,and it was 4.44%(2/46)in the conventional group;there was no statistical difference in adverse reaction rate between the two groups(P>0.05).The recurrence rate within 6 months was 0.00%(0/46)in the acupuncture group,which was lower than 8.89%(4/45)in the conventional group(P<0.05).Conclusion:The treatment of PHN with modified Qinglong wagging tail acupuncture is very good,the symptoms of patients are significantly improved,the pain is relatively relieved,the quality of sleep and life is better,the adverse reactions are less,and the recurrence rate is lower within 6 months,which is worthy of application.