摘要
非自杀性自伤(NSSI)多发生在青少年和成年早期,与情绪相关疾病发生率增高及发展至难治性等相关,是自杀的重要危险因素。NSSI人群其内分泌和免疫发生一些变化,探讨NSSI发生的内分泌免疫机制,可能有助于NSSI早期预防与干预。本文从下丘脑-垂体-肾上腺轴(HPA轴)、下丘脑-垂体-甲状腺轴(HPT轴)、下丘脑-垂体-性腺轴(HPG轴)及免疫炎症与NSSI发生的相关研究进展作一综述。
Non-suicidal self-injury(NSSI),being one of the most important suicide risk factors,mostly oc-cur in adolescent and early adulthood,which is related to the mood disorder and move forward to treatment re-sistant.People with NSSI have some changes in endocrine-immune.Exploring the mechanism on endocrine-im-mune for NSSI will help to earlier prevention and intervention.This article will review the research progress for NSSI on the following endocrine-immune aspects such as hypothalamic-pituitary-adrenal axis(HPA),hypotha-lamic-pituitary-thyroid axis(HPT),hypothalamic-pituitary-gonadal axis(HPG)and the immune inflammation.
作者
周洛慧
苏颖芮
柳绪珍
孙静
ZHOU Luo-hui;SU Ying-rui;LIU Xu-zhen;SUN Jing(Nanjing Medical University,Nanjing 210029,China)
出处
《临床精神医学杂志》
CAS
2024年第1期78-80,共3页
Journal of Clinical Psychiatry
基金
南京市卫生科技发展项目(YKK22141)