男性乳腺肿块的超声造影特征

Contrast-enhanced ultrasound features of male breast masses

目的探讨男性乳腺肿块的超声造影特征。方法收集2014年1月至2020年10月因发现乳腺肿块在浙江大学医学院附属杭州市胸科医院就诊的男性患者6例,所有病例均经病理结果证实。分析男性乳腺肿块的超声及超声造影特征表现。结果6例男性乳腺肿块均为单侧发病,病理证实3例为浸润性导管癌,3例为男性乳腺增生。二维超声表现:6例乳腺肿块均呈低回声。3例乳腺癌患者均可探及血流信号,其中2例可见粗大扭曲血管,1例乳腺癌内见多发微钙化。3例乳腺增生中1例可见条状血流信号,均未发现微钙化。超声造影表现:3例男性乳腺癌超声造影均表现不均匀增强及灌注缺损,而乳腺增生无此特征。3例乳腺癌与2例乳腺增生增强后范围均较二维超声范围扩大,1例乳腺增生增强范围不清。结论男性乳腺增生与男性乳腺癌具有不同的造影特征,不均匀增强及灌注缺损等超声造影特征在男性乳腺癌中表现出潜在的诊断价值,可为临床提供更多的诊断信息。

Objective To evaluate the value of contrast-enhanced ultrasonography in the diagnosis of male breast masses.Methods A retrospective study was performed on the medical records of 6 male patients with breast masses diagnosed at the Affiliated Hangzhou Chest Hospital of Zhejiang University School of Medicine from January 2014 to October 2020.All patients were finally diagnosed by pathological results.Results All 6 cases of male breast masses were unilateral.Pathology confirmed 3 cases of invasive ductal carcinoma and 3 cases of male breast hyperplasia.Convention ultrasound showed that all the 6 breast masses were hypoechoic.Blood flow signals can be detected in 3 cases of breast cancer,including 2 cases with coarse twisted blood vessels and 1 case with multiple microcalcifications in breast cancer.No microcalcification was found in 1 of 3 cases of breast hyperplasia.Contrast-enhanced ultrasonography revealed that 3 cases of male breast cancer showed uneven enhancement and perfusion defect,but breast hyperplasia did not have this characteristic.Three cases of breast cancer and two cases of breast hyperplasia had expanded enhancement range on contrast-enhanced ultrasound compared to the lesion range detected by conventional ultrasound,while the enhancement range of 1 case of breast hyperplasia was unclear.Conclusion Male breast hyperplasia and male breast cancer have different contrast characteristics.Contrast-enhanced ultrasound features such as uneven enhancement and perfusion defect show potential diagnostic value for male breast cancer,which can provide more diagnostic information for clinicians.