曲靖地区女性阴道分泌物常规与生化检测结果分析

Analysis of routine and biochemical testing results of female vaginal secretions in Qujing area

目的探讨阴道分泌物常规联合生化五项检测的临床价值。方法收集曲靖市第一人民医院2019年9月-2022年12月共48107例妇科门诊患者的阴道分泌物常规与生化检测结果,分析该地区女性阴道微生态现状及影响因素。结果48107例阴道分泌物标本中,正常清洁度(I~II度)占43.25%、异常清洁度(III~IV度)占56.75%;滴虫检出971例(2.02%),检出真菌4401例(9.15%),检出线索细胞3120例(6.49%),同时检出滴虫和真菌11例,同时检出滴虫和线索细胞62例,同时检出真菌和线索细胞242例。不同年龄组间滴虫、真菌、线索细胞、白细胞、阴道杆菌、球菌、上皮细胞和清洁度差异均有统计学意义(P<0.05);不同季节间真菌、线索细胞的检出率差异也有统计学意义(P<0.05)。滴虫检出率无季节差异(P>0.05)。过氧化氢、唾液酸苷酶、白细胞酯酶、β-葡萄糖醛酸苷酶、凝固酶阳性率分别为76.08%、11.19%、42.24%、0.80%、31.57%。不同清洁度间生化五项指标差异有统计学意义(P<0.05)。结论曲靖地区女性阴道分泌物病原体检出率较高,常规联合生化检测可提高阴道炎诊断准确率,加强女性尤其低龄和围绝经期女性的健康指导与生殖道感染监测,意义重大。

Objective To explore the clinical value of routine combined with five biochemical tests of vaginal secretions.Methods The routine and biochemical testing results of vaginal secretions from 48,107 gynecological outpatients in the First People s Hospital of Qujing from September 2019 and December 2022 were collected,and analyzed current status and influencing factors of female vaginal microecosystem in this area.Results Among the 48107 samples of vaginal secretions,43.25%were normal cleanliness(I-II degree)while 56.75%showed abnormal cleanliness(III-IV degree).The trichomonas were detected in 971 cases(2.02%),fungi were detected in 4401 cases(9.15%)and clue cells were detected in 3120 cases(6.49%).Trichomonas and fungi were detected concurrently in 11cases,while trichomonas and clue cells were detected simultaneously in 62 cases.Both fungi and clue cells were detected in 242 cases.There were statistical significance in trichomonas,fungi,clue cells,white blood cells,vaginal bacilli,vaginal bacillus,cocci,epithelial cells and cleanliness among different age groups(P<0.05).The detection rates of fungi and clue cells in different seasons also had statistical significance(P<0.05),there was no significant difference in the detection rate of trichomonas(P>0.05).The positive rates of hydrogen peroxide(H 2O 2),sialidase(SNa),leukocyte esterase(LE),β-glucuronidase(GUS)and coagulase(GADP)were 76.08%,11.19%,42.24%,0.80%and 31.57%,respectively.There were statistical significance in five biochemical indicators of different cleanliness(P<0.05).Conclusions The pathogen detection rate of female vaginal secretions in Qujing area is high.Routine combined biochemical testing can enhance the accuracy of vaginitis diagnosis,and strengthen health guidance and monitoring of reproductive tract infection for women,particularly young or perimenopausal women.