摘要
目的研讨Hs-cTnT、BNP水平与ACS患者住院转归的相关性。方法选取曲靖市第一人民医院2022年1月-2022年12月收住的ACS患者1185例作为研究组,选取同期收住的1000名非器质性心脏病患者作为对照组。采集患者基线资料和临床转归情况,对比2组患者血清Hs-cTnT、BNP测值的差异。结果研究组Hs-cTnT、BNP测值均高于对照组(0.07±0.01 VS 51.12±3.21,P<0.05);研究组中不稳定心绞痛、ST段抬高心梗、非ST段抬高心梗三个亚组间临床不良转归与血清BNP测值存在相关性(1%VS 1%VS 1%,P<0.05)。Hs-cTnT测值在ST段抬高心肌梗死与非ST段抬高心肌梗死预后理想与预后不理想亚组间存在相关性(0.023 VS 0.009,P<0.05);而不稳定心绞痛预后理想与预后不理想组间血清Hs-cTnT测值无显著性差异(0.062,P>0.05)。结论血清Hs-cTnT、BNP对ACS患者的疾病严重程度、预后转归具有良好的预测价值,两者联合应用价值更高,血清BNP测值的转归预测价值更高。
Objective To investigate the correlation between serum levels of highly sensitive troponin T(Hs-cTnT)and brain natriuretic peptide(BNP)and hospitalization outcomes in ACS patients.Methods A total of 1185 ACS patients admitted to Qujing First People s Hospital from January 2022 to December 2022 were selected as the research group,and 1000 non-organic heart disease patients admitted during the same period were selected as the control group.Collected baseline data and clinical outcomes of the patients,and compared the differences in serum Hs-cTnT and BNP measurements between the two groups of patients.Results The Hs-cTnT and BNP measurements in the research group were higher than those in the control group(0.07±0.01 VS 51.12±3.21,P<0.05);In the research group,there was a correlation between the clinical adverse outcomes of unstable angina pectoris,ST segment elevation myocardial infarction and non-ST segment elevation myocardial infarction measurements among the three subgroups and serum BNP(1%VS 1%,P<0.05).There was a correlation between the Hs-cTnT measurement values in the subgroups of ST segment elevation myocardial infarction and non-ST segment elevation myocardial infarction with ideal and poor prognosis(0.023 VS 0.009,P<0.05);There was no significant difference in serum Hs-cTnT values between the groups with ideal and poor prognosis for unstable angina(0.062,P>0.05).Conclusions Serum Hs-cTnT and BNP have good predictive value for disease severity and prognosis in ACS patients,and their combined value is higher.Serum BNP measurements have higher predictive value for prognosis.
作者
李卓
蒋小丽
LI Zhuo;JIANG Xiao-li(Department of Cardiovascular Medicine,Qujing Municipal First People's Hospital,Qujing Yunnan 655000,China)
出处
《云南医药》
CAS
2024年第1期55-58,共4页
Medicine and Pharmacy of Yunnan
关键词
急性冠脉综合征
血清高敏肌钙蛋白T
脑钠肽
acute coronary syndrome
serum hypersensitive troponin T
brain natriuretic peptide