药学干预对呼吸科门急诊抗菌药使用的影响

Influence of Pharmacy Intervention in the Rational Use of Antimicrobials in Respiratory Outpatient and Emergency Departments

目的探讨基于合理用药监测系统(prescription automatic screening system,PASS)的处方点评与药学干预对呼吸与危重症科门急诊抗菌药物合理应用的影响。方法将2021年8月至2023年8月天津市胸科医院呼吸与危重症科门急诊使用抗菌药物的20270份处方作为研究对象。将2022年8月开始进行药学干预的处方作为干预组,干预之前的处方作为对照组。利用PASS系统对全部处方进行抽样,临床药师进行处方点评,对点评不合格处方进行合理性分析,将点评结果反馈医师并针对点评结果在全科范围内进行抗菌药物合理使用培训。结果干预组处方合格率显著高于对照组,差异有统计学意义(P<0.05),且随着药学干预时间的延长稳步增长。结论药学干预有助于提升呼吸与危重症科门急诊抗菌药物的合理应用。

Objective To explore the influence of prescription review and pharmaceutical intervention based on prescription automatic screening system(PASS)on rational use of antibiotics in respiratory critical and emergency departments.Methods From August 2021 to August 2023,20270 prescriptions of antibiotics used in respiratory and critical care departments and emergency departments of Tianjin Chest Hospital were studied.The prescriptions for pharmaceutical intervention starting in August 2022 were taken as the intervention group,and the prescriptions before the intervention were taken as the control group.The PASS system was used to sample all prescriptions,clinical pharmacists made prescription comments,and analyzed the reasonableness of unqualified prescriptions.The comments were fed back to physicians and the rational use of antimicrobials was trained in the whole department based on the comments.Results The qualified rate of prescription in the intervention group was significantly higher than that in the control group,the difference was statistically significant(P<0.05),and it increased steadily with the time of pharmaceutical intervention.Conclusion Pharmaceutical intervention is helpful to improve the rational use of antibiotics in respiratory,critical and emergency departments.