宫颈癌腹主动脉旁淋巴结的影像诊断及放射治疗研究进展

Research progress of imaging diagnosis and radiotherapy in para-aortic lymph nodes of cervical cancer

宫颈癌是全世界最常见的妇科恶性肿瘤之一。对于宫颈癌,最新修订的国际妇产科联盟(FIGO)分期系统(2018)在其分期中纳入了影像学和病理学评估。在妇科检查的基础上严格对宫颈癌进行临床分期,新增盆腔淋巴结受累的肿瘤ⅢC1期,腹主动脉旁淋巴结受累的肿瘤ⅢC2期。根据《美国国家综合癌症网络肿瘤临床实践指南》,盆腔/腹主动脉旁淋巴结转移的患者是化疗和放疗的候选对象,而不是手术。然而目前有关影像学诊断及放射治疗的标准仍有一定争议。本篇综述总结宫颈癌腹主动脉旁淋巴结的影像学诊断以及目前放射治疗进展。

Cervical cancer is one of the most common gynecological malignancies in the world.For cervical cancer,the latest revised International Federation of Gynecology and Obstetrics(FIGO)staging system(2018)includes imaging and pathological evaluation in its staging.On the basis of gynecological examination,the clinical stage of cervical cancer is strictly carried out,and the tumor stageⅢC1 with pelvic lymph node involvement and the tumor stageⅢC2 with para-aortic lymph node involvement are newly added.According to the National Comprehensive Cancer Network Clinical Practice Guidelines for Oncology,patients with pelvic/para-aortic lymph node metastasis are candidates for chemotherapy and radiotherapy,not for surgery.However,the current standards for imaging diagnosis and radiotherapy are still controversial.In this review,the imaging diagnosis of para-aortic lymph nodes in cervical cancer and the current progress of radiotherapy are summarized.