穴位埋线联合阿托伐他汀治疗单纯性肥胖合并高脂血症患者的疗效研究

The therapeutic Effect of Acupoint Thread embedding combined with Atorvastatin on Patients with simple Obesity and Hyperlipidemia

目的探讨穴位埋线联合阿托伐他汀治疗单纯性肥胖合并高脂血症患者的疗效。方法选取2022年5月至2023年5月河南省直属机关第一门诊部收治的单纯性肥胖合并高脂血症患者60例,根据随机数表法将患者分为对照组(实施阿托伐他汀治疗),联合组(在对照组的基础上联合穴位埋线治疗),每组患者各30例,两组患者均持续治疗2个月。比较两组患者临床疗效、治疗前后的体重、体质量指数(BMI)、腰围、血脂水平、炎性因子水平、不良反应发生率。结果治疗2个月后,联合组治疗有效率(93.33%)高于对照组(73.33%),差异有统计学意义(P<0.05);治疗2个月后,联合组的体重、BMI、腰围较对照组低,差异有统计学意义(P<0.05);治疗2个月后,联合组的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)较对照组低,高密度脂蛋白(HDL-C)高于对照组,差异有统计学意义(P<0.05);治疗2个月后,联合组的炎性因子水平白介素-6(IL-6)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)与对照组相比降低,差异有统计学意义(P<0.05);联合组的不良反应发生率(13.33%)与对照组的不良反应发生率(26.67%)比较,差异无统计学意义(P>0.05)。结论在单纯性肥胖伴有高脂血症的基础上采用阿托伐他汀联合穴位埋线,具有降低患者体重,调整患者血脂水平,降低炎症反应的作用,具有良好的临床疗效。

Objective To explore the therapeutic effect of acupoint thread embedding combined with atorvastatin on patients with simple obesity and hyperlipidemia.Methods A total of 60 patients with simple obesity and hyperlipidemia admitted to the First Outpatient Department of Henan Province's directly affiliated institutions from May 2022 to May 2023 were selected.According to the random number table method,the patients were divided into control group(treated with atorvastatin)and combination group(treated with acupoint embedding thread on the basis of the control group),with 30 patients in each group.Both groups of patients were treated continuously for 2 months.The clinical efficacy,body weight,body mass index(BMI),waist circumference,blood lipid levels,inflammatory factor levels,and incidence of adverse reactions between two groups of patients were compared before and after treatment.Results After 2 months of treatment,the effective rate of the combination group(93.33%)was higher than that of the control group(73.33%),and the difference was statistically significant(P<0.05);After 2 months of treatment,the weight,BMI,and waist circumference of the combination group were lower than those of the control group,and the differences were statistically significant(P<0.05);After 2 months of treatment,the total cholesterol(TC),triglycerides(TG),and low-density lipoprotein(LDL-C)in the combination group were lower than those in the control group,while high-density lipoprotein(HDL-C)was higher than those in the control group,with statistical significance(P<0.05);After 2 months of treatment,the levels of inflammatory factors such as interleukin-6(IL-6),C-reactive protein(CRP),and tumor necrosis factor-α(TNF-α)in the combination group were significantly lower than those in the control group,the difference was statistically significant(P<0.05);The incidence of adverse reactions in the combination group(13.33%)was not significantly different from that in the control group(26.67%)(P>0.05).Conclusion On the basis of simple obesity accompanied by hyperlipidemia,the use of atorvastatin combined with acupoint thread embedding has the effect of reducing patient weight,adjusting patient blood lipid levels,and reducing inflammatory reactions,and has good clinical efficacy.