瞬时弹性成像技术诊断自身免疫性肝炎的价值研究

Study on the value of transient elastography for the diagnosis of autoimmune hepatitis

目的:应用瞬时弹性成像技术研究自身免疫性肝炎的肝硬度特点,比较该技术诊断自身免疫性肝炎和乙肝肝硬度值的差异。方法:回顾性分析2020年11月—2021年12月于江南大学附属无锡五院经临床确诊的40例自身免疫性肝炎患者和50例乙肝患者的肝脏硬度特点,记录样本的肝硬度值与肝纤维化病理分期,比较肝硬度值与病理分期的相关性和差异性。结果:自身免疫性肝炎肝纤维化越重,肝硬度值越大。重度肝纤维化(S3~S4)时,自身免疫性肝炎和乙肝的肝硬度值差异有统计学意义(P<0.05)。结论:瞬时弹性成像技术诊断自身免疫性肝炎有一定的临床价值。

Objective Using transient elastography to study the characteristics of liver stiffness of autoimmune hepatitis,and compare the difference of liver stiffness between autoimmune hepatitis and hepatitis B.Methods Retrospective analysis was made on the liver stiffness characteristics of 40 patients with autoimmune hepatitis and 50 patients with hepatitis B who were clinically diagnosed in the Affiliated Wuxi Fifth Hospital of Jiangnan University from November 2020 to December 2021.The liver hardness values of the samples and the pathological stages of liver fibrosis were recorded,and the correlation and difference between the liver stiffness values and the pathological stages were compared.Results The liver stiffness values of autoimmune hepatitis increased with the aggravation of the pathological stage of liver fibrosis.The difference between the liver stiffness values of autoimmune hepatitis and hepatitis B was statistically significant when the pathology showed severe liver fibrosis(S3~S4)(P<0.05).Conclusion Transient elastography has a certain application value in the diagnosis of autoimmune hepatitis.