儿童血管迷走性晕厥的治疗进展

Research progress of treatment for vasovagal syncope in children

血管迷走性晕厥(VVS)为儿童晕厥最常见的病因,约占所有晕厥事件的50%以上,发作频繁常影响儿童的正常生活和学习,需要积极干预预防晕厥的发作。如何选择个体化的治疗方案以提高疗效、降低复发率是目前研究的热点,治疗方案也从经验治疗逐渐转向基于血流动力学和生物标志物的个体化精准治疗。本文从VVS的非药物治疗、药物治疗及介入治疗三大方面回顾其治疗进展,以期 促进儿童VVS治疗策略的深入研究。

Vasovagal syncope(VVS)is the most common cause of syncope in children,accounting for more than 50%of all syncope events.Frequent attacks of VVS often affect children′s normal life and learning,so effective intervention is needed to prevent the onset of syncope.Selection of individualized therapeutic protocol to improve efficacy and reduce recurrence rate is a hotspot in current research.Currently,the treatment has gradually shifted from empirical treatment to individualized precision therapy based on hemodynamics mechanism and therapeutic efficacy biomarkers.This review summarized the progress of VVS treatment from three aspects:non-drug therapy,drug therapy and interventional therapy,in order to promote the further study of the treatment strategy for children with VVS.